Fog Pharmaceuticals, Inc.

So Youn Shim

Gregory Lawrence Verdine

Gerard Hilinski

John Hanney McGee

Paula Cristina Ortet

Matthew Reiser Patton

Among other things, the present disclosure provides technologies for modulating functions of beta-catenin. In some embodiments, the present disclosure provides stapled peptides that interact with beta-catenin. In some embodiments, provided stapled peptides interact with beta-catenin at an Axin-binding site of beta-catenin. In some embodiments, the present disclosure provides compounds, compositions and methods for preventing and/or treating conditions, disorders and diseases that are associated with beta-catenin.

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Watertown, MA, United States of America

So Youn Shim