Chonnam National University

Jeonnam Technopark

So Youn Lee

Myung Ho Jeong

Dae Sung Park

Eun Jae Jang

Kyung Seob Lim

In-Ho Bae

Jun Kyu Park

Jae Won Shim

In Soo Kim

Doo Sun Sim

In Ho Bae

Kwang Hwan Oh

A tacrolimus drug-eluting stent manufacturing method according to the present invention enables a tacrolimus drug to be strongly and stably bound onto a stent, while also not necessarily involving a separate step of introducing a surface-binding functional group for the binding of a drug onto a stent and a step of introducing, into the drug, a functional group capable of binding to the surface-binding functional group, and a tacrolimus drug-eluting stent manufactured by the manufacturing method has a greater total drug elution amount and has a more excellent delayed drug-elution property.

Non-polymeric tacrolimus drug-eluting stent and manufacturing method therefor

Provided is a drug-eluting coronary stent. In the drug-eluting coronary stent according to the present invention, electrospinning is used, thereby making it possible to precisely control a total content of an everolimus-based drug bound thereto and form a uniform layer in spite of not using a polymer causing late thrombosis, or the like.

Method of manufacturing polymer-free everolimus-eluting coronary stent fabricated by electrospinning technique

Provided are a stent in which a surface of a stent strut is treated by femtosecond laser radiation and is modified by a natural polymer and a method of preparing the stent. The stent and the preparing method may inhibit restenosis and stimulate reendothelialization.

Stent for inhibiting restenosis and stimulating reendothelialization prepared by femtosecond laser processing and method of preparing the same

Provided are a peptide compound prepared by additional synthesis in a drug having an effect of inhibiting restenosis, a composition for inhibiting restenosis and promoting re-endothelialization including the peptide compound, and a stent having a surface coated by using the composition, in order to overcome a restenosis problem in the stent.

Peptide compound for inhibiting restenosis and promoting re-endothelialization and method for preparing the same

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Gwangju, South Korea

So Youn Lee