Yonsei University

So-hee Han

Yong-beom Lim

The present disclosure relates to a self-assembled peptide nanostructure including at least one amphiphilic peptide and a biosensor using the same. The amphiphilic peptide is a hairpin-shaped amphiphilic peptide including a hydrophilic domain having an &#x3b1;-helical structure and a hydrophobic domain. The N-terminal of the hydrophobic domain is a pyrene group. Since the self-assembled peptide nanostructure is derived from an RNA, DNA or amino acid sequence capable of recognizing a specific target substance, it does not recognize other substances but exhibits high selectivity for the target substance. Specifically, since the self-assembled peptide nanostructure has an excimer fluorescence peak at 480 nm through binding with the target substance, it can be usefully used in medical applications such as diagnosis of diseases.

Self-assembled peptide nanostructures by exploiting conformational change, biosensor using the same and detection method of biomolecules using the same

Growing community of inventors

Seoul, South Korea

So-hee Han