Arch Personal Care Products L.p.

Allergan, Inc.

Arch Personal Care Product, LP

Smitha Rao

James Vincent Gruber

Geoffrey Brooks

Rahul C Mehta

Sujatha Sonti

Geoffrey Jamison Brooks

Disclosed herein is a topical composition that contains a fermentation extract from a simultaneous or sequential fermentation. When topically applied to skin, the composition of the invention is effective in stimulating the production of hyaluronic acid, CD44 and Caspase 14 protein in skin cells.

Composition containing an extract of a sequential or simultaneous fermentation

Compositions comprising metabolized conditioned growth medium and/or metabolized cell extract and methods of use are described. The metabolized conditioned growth medium and metabolized cell extract compositions may be formulated with an acceptable carrier into injectable or topical formulations, for example, as a cream, lotion or gel, and may be used in cosmeceutical or pharmaceutical applications. The metabolized conditioned growth medium and metabolized cell extract may also be further processed to concentrate or reduce one or more factors or components contained within the metabolized conditioned growth medium or metabolized cell extract. The growth medium may be conditioned by any eukaryotic cell. The metabolized conditioned growth medium and metabolized cell extract may be used to prevent or treat a condition, for example, a skin condition.

Process for preparing metabolized conditioned growth media

A method of producing yeast-polyphenol ferment extract includes growing the cells of a yeast ofgenus in a growth media to late-logarithmic growth phase, in which the carbon source in the media is exhausted; exposing the cells to a non-cytotoxic dose of polyphenol; and extracting cytoplasmic and extra-cellular components of the exposed yeast cells from the growth media.

Personal care composition containing yeast/polyphenol ferment extract

Topical composition

Disclosed is a yeast/polyphenol ferment extract, and a personal care composition including the yeast/polyphenol ferment extract. Also disclosed is a method for preparing and using the yeast/polyphenol extract and the personal care composition.

Growing community of inventors

Hillsborough, NJ, United States of America

Smitha Rao