Industria E Comércio De Cosméticos Natura Ltda.

Natura Cosméticos S.a.

Simoni Chitarra Souza

Philippe Joseph Pommez

Roberto Alcantara Martins Zucchetti

Luciana Villa Nova Silva

Rodrigo Fuscelli Pytel

Simone Fanan

Luiz Gustavo Martins Matheus

Karla Araujo Macian

Karla De Souza Ara&uacute;jo

Roberto Alcantara Zucchetti

Karla De Souza Araujo

The present invention is directed to a process for stabilizing antioxidant compounds comprising the step of adding to said compound, in an aqueous mean, at least an oxygen-removing compound, at least a metallic ion sequestering compound and at least an oxidation reaction reversing compound. The invention is particularly useful to stabilize antioxidant compounds such as levogyrous ascorbic acid (LAA), popularly known as 'Vitamin C', and the LAA associated with proantocianidines (OPC) for the preparation of pharmaceutical and cosmetic compositions.

Process for stabilizing antioxidant compounds, and aqueous compositions

The present invention refers to a process, a composition and the use of Vitamin C for enhancing the action of Vitamin A on the cellular activity of an individual. According to the invention, the association of Vitamin C to Vitamin A will be applied to said individual at a weight ratio ranging from 1:1 to about 10:1.

Process and composition for enhancing the action of vitamin a on the cellular activity of an individual, and use of vitamin c

The present invention refers to a process for stabilizing LAA in an aqueous medium, which includes the step of contacting the LAA with at least one-compound capable of forming hydrogen bridges with the LAA. In another aspect, the invention relates to a stable aqueous LAA composition which includes, in addition to the ascorbic acid, at least one compound which is linked to the LAA by hydrogen bridges, and to a process for preparing it. The present invention further relates to an emulsion including, in its aqueous phase, at least one compound linked to levogyre ascorbic acid (LAA) by hydrogen bridges. Further according to the present invention a vitamin product is provided, in which a stable LAA composition as described above is contained in organic envelopes which enable a gradual and prolonged release of the LAA into the organism. The vitamin product may further include a compound capable of stimulating the metabolism of the fibroblasts. The present invention further relates to a method for cosmetic, therapeutical or nutritional treatment, which includes the administration of a composition as described above.

PROCESS FOR STABILIZING LEVOGYRE ASCORBIC ACID (LAA), A STABLE AQUEOUS LAA COMPOSITION, A PROCESS FOR PREPARING A STABLE TOPICAL SOLUTION, AN EMULSION, A VITAMIN PRODUCT, AND A METHOD FOR COSMETIC, PHARMACEUTICAL OR NUTRITIONAL TREATMENT

The present invention refers to a process for stabilizing LAA in an aqueous medium, which includes the step of contacting the LAA with at least one compound capable of forming hydrogen bridges with the LAA. In another aspect, the invention relates to a stable aqueous LAA composition which includes, in addition to said ascorbic acid, at least one compound which is linked to the LAA by hydrogen bridges, and to a process for preparing it. The present invention further relates to an emulsion including, in its aqueous phase, at least one compound linked to levogyre ascorbic acid (LAA) by hydrogen bridges. Further according to the present invention a vitamin product is provided, in which a stable LAA composition as described above is contained in organic envelopes which enable a gradual and prolonged release of the LAA into the organism. The vitamin product may further include a compound capable of stimulating the metabolism of the fibroblasts. The present invention further relates to a method for cosmetic, therapeutical or nutritional treatment, which includes the administration of a composition as described above.

Process for stabilizing levogyre ascorbic acid (LAA), a stable aqueous

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São Paulo, Brazil

Simoni Chitarra Souza