Noxxon Pharma Ag

Simone Schulzchen

Sven Klussmann

Christian Maasch

Florian Jarosch

Werner Purschke

Kai Hohlig

The present invention is related to a nucleic acid molecule capable of binding to CGRP, wherein the nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5' HWnnYGGAnAnUMnnYnnnnnKnRnADnnARnUnCnnUnn3&#x2032; [SEQ ID NO: 99], wherein H, W, Y, G, A, U, M, B, K, R, D, C are ribonucleotides, and nis R or dG, nis U or dT, nis K or dG, nis C or dC, nis M or dC, nis B or dU, nis N or dG, nis Y or dT, nis N or dC, nis R or dG, nis V or dA, nis K or dT or dU, nis G or dG, nis A or dA, nis U or dT, nis R or dG, nis Y or dC, nis C or dC, nis B or dC, nis C or dC, nis C or dC, and dG, dT, dC, dA and dU are 2&#x2032;-deoxyribonucleotides.

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Berlin, Germany

Simone Schulzchen