Annikki Gmbh

Technische Universitat

Simone Knaus

Heinrich Gruber

Alexander Poschalko

Kerstin Wallisch

Thomas Verdianz

The present invention relates to a method for the preparation of a lignin prepolymer, comprising (a) providing a lignin; (b) reacting the lignin with a hydroxyl functionalization reagent to provide a lignin derivative containing at least one hydroxyl group, said hydroxyl group being obtained as a result of the interaction between the lignin and the hydroxyl functionalization reagent (c) reacting the lignin derivative obtained in step (b) with a functionalization reagent selected from the group consisting of fatty acids, fatty acid derivatives and mixtures thereof capable to react with the lignin derivative resulting in a covalent bond between the fatty acid and/or or the fatty acid derivative and the lignin derivative.

Method for the preparation of a lignin prepolymer

The invention relates to methods for the production of polymer carrier materials for solid phase synthesis, particularly for peptide synthesis. (Meth)acrylamide derivatives based on carbon hydrates, which can also contain other protective groups, are polymerized by means of suspension polymerization in an aqueous phase, optionally with the addition of pore-forming additives, and subsequently the protective groups are fully or partially cleaved. It is thus possible to obtain polymer carriers whose morphology (particle size, porosity), degree of cross-linking and swelling capability in aqueous and organic media can be adjusted in a targeted manner and whose reactive groups offer multiple opportunities for the immobilization of anchor groups and protective groups. The hydroxyl groups of the polymer carrier can be activated according to usual methods of solid phase synthesis.

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Vienna, Austria

Simone Knaus