Sterix Limited

Simon Paul Newman

Michael John Reed

Barry Victor Lloyd Potter

Atul Purohit

Matthew Paul Leese

Fabrice Jourdan

Surinder Kuman Chander

Paul Alexander Foster

Sarah Louise Claire Tagg

The present invention provides a compound comprising a steroidal ring system and an optional group Rselected from any one of &#x2014;OH, a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; wherein the D ring of the steroidal ring system is substituted by a group Rof the formula -L-R, wherein L is an optional linker group and Ris selected from groups which are or which comprise one of a nitrite group, an alcohol, an ester, an ether, an amine and an alkene, provided that when Ris or comprises an alcohol, L is present; and wherein the A ring of the steroidal ring system is substituted at position 2 or 4 with a group R, wherein Ris a hydrocarbyl group.

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Slough, United Kingdom

Simon Paul Newman