The University of British Columbia

Qlt Inc.

Quadra Logic Technologies, Inc.

Simon Leong

Julia G Levy

Agnes How-Ching Chan

Martin Renke

Anna M Richter

Janice North

David W Hunt

David William Carey Hunt

Philippe Maria Margaron

Multiple sclerosis and rheumatoid arthritis can be treated effectively using photodynamic therapy. In this protocol, a photoactive compound is administered, allowed to distribute in the effected subject, and the subject is then irradiated to activate the photoactive compound. Alternatively, the blood of a subject to be treated can be subjected to PDT extracorporeally. In the case of rheumatoid arthritis, localized treatment at the joints may also be employed.

Photodynamic therapy in selective cell inactivation in blood and treating immune dysfunction diseases

The invention provides a method to inhibit the formation of neovasculature while maintaining viability of the underlying tissue by subjecting a subject in which angiogenesis is to be inhibited to sublethal photodynamic therapy. The invention also provides a model for assessing sublethal PDT protocols to inhibit angiogenesis in particular target tissues.

Model and method for angiogenesis inhibition

Method for selectively reducing activated leukocyte cell population

Growing community of inventors

Burnaby, Canada

Simon Leong