Cana Technology, Inc.

Argos Therapeutics, Inc.

Ventana Medical Systems, Inc.

Genea IP Holdings Pty Limited

Kyowa Hakko Kirin Co., Limited

Kirin Pharma Kabushiki Kaisha

Coimmune, Inc.

Timothy Doyle Peele

Richard Alexander Grant

Ashraf F. Abdelmoteleb

David Thomas Kneen

Simon Jonathon Spence

Robert Alister Neil

William Samuel Hunter

Simon Harris

Erik James Shahoian

Gregory Allen Springer

Matthew Ambauen

David Friedberg

Stephan Weidi Tai

Peter Delmenico

Jeffery Lance Kizer

Andrés Ornelas Vargas

Andrew Christopher Jenkins

Nathan Andrew Ray

Ashraf Farid Abdelmoteleb

Kristopher Bernardo Dos Santos

Brian Howard Kram

Kevin David Marshall

Matthew Ketterer

Elijah S Kashi

Benjamin James

Donald Michael Barnett

Andrew Scott Davies

Timothy Durrant

Danilo Bueno

Timothy Brett McDonald

Joshua David Kenneth Harrison

Luke Dyson-Holland

Daniel C Malberg

Eduardo Vom

John Douglas Willems, Jr

Henning Groll

Austin Micheil Ashby

Nicholas D Posner

Kevin Talucci

Samuel Ross Garland Lanyon

Jessica A Wifall

Dale Word

Mirek Holubec

Jessica Jones

Sean McCommons

Benedict John Stewart-Steele

John Willems

Simon Davies

Jasmine Pouladi

Adrian Higgins

Sacha Marie Dopheide

Patrick Brown

Lizhen Pang

Bryan Barnes

Andrew Watkins

Sacha Dopheide

Yassaman Pouladi

Ben Stewart-Steele

Ashraf F Abdelmoteleb

Ben James

Benjamin Arthur James

Timothy James Durrant

At least some embodiments of the technology are directed to an automated slide processing apparatus configured to apply at least one reagent to a specimen carried by a microscope slide. The slide processing station can include a support element with a support surface, at least one vacuum port, and a sealing member having a non-round shape. In an uncompressed state, the scaling member can extend upwardly beyond the support surface. In a compressed state, the scaling member can be configured to maintain an airtight seal with a backside of the microscope slide as the microscope slide is pulled against the support surface by a vacuum drawn via the at least one vacuum port.

Specimen processing systems and methods for holding slides

A cartridge and an associated beverage mixture dispensing system are disclosed. The cartridge is detachable from the associated beverage mixture dispensing system. The cartridge includes a casing and at least twenty ingredient reservoirs located within the casing and storing at least twenty respective ingredients. The cartridge also includes a dispensing interface for dispensing the at least twenty ingredients into the beverage mixture dispensing system. The at least twenty ingredient reservoirs include a first reservoir of a concentrated salt and a second reservoir of a concentrated food grade acid. The remaining ingredient reservoirs include additional concentrated ingredients. The beverage mixture dispensing system includes a solvent reservoir and a receiving interface for receiving the at least twenty ingredients from the cartridge. The beverage mixture dispensing system also includes a mixing area fluidly connected to the solvent reservoir and the at least twenty ingredient reservoirs.

Ingredients cartridge for a beverage mixture dispensing system

Systems and methods for sanitizing a fluid mixture dispensing system are disclosed. One system comprises at least one reservoir for storing a substance, a mixing area, and a controller. The controller is programmed to cause the system to execute a mixing cycle and a cleaning cycle. During the mixing cycle the substance is dispensed from the at least one reservoir to the mixing area to prepare an ingestible fluid mixture. During the cleaning cycle, the substance is dispensed from the at least one reservoir to the mixing area to sanitize the mixing area.

Sanitizing systems and methods for fluid mixture dispensing device

A fluid mixture dispensing system using a membrane to seal multiple reservoirs is disclosed. The multiple reservoirs each contain a respective ingredient. The reservoirs are coupled to respective orifices in a plate. The respective ingredients are dispensable via the respective orifices. The membrane seals the respective orifices. The ingredients are dispensed into one or more channels formed between the membrane and the plate. In specific embodiments, the membrane is an integral part of a cartridge which contains the multiple reservoirs. In specific embodiments, the cartridge includes an inlet and an outlet. A solvent flows from the inlet to the outlet through the one or more channels, and the ingredients are dispensed into the solvent in the one or more channels.

Membrane for reservoir seals in fluid mixture dispensing system

Ingredient dispensing systems and methods in a fluid mixture system using a monitored chamber pressure are disclosed. One system includes a chamber, an inlet to the chamber, a set of ingredient reservoirs, in the chamber, storing a respective set of ingredients and sealed by a respective set of valve, a pressure source, and a controller. The system is programmed to set a pressure of the chamber using the pressure source and the inlet to the chamber. The system is also programmed to dispense, using the pressure, at least two ingredients from the respective set of ingredients by actuating at least two valves from the respective set of valves.

Ingredient dispensing in a fluid mixture system using monitored pressure

Fluid mixture dispensing systems, devices and methods are disclosed. A device includes a set of pressurized ingredient reservoirs, a mixing area configured to receive at least one ingredient from the set of pressurized ingredient reservoirs, a pressure source, an accumulator chamber, a set of valves, and a controller. The controller is programmed to operate the set of valves to pressurize the accumulator chamber using the pressure source. The controller is further programmed to operate the set of valves to set a pressure in at least one of the set of pressurized ingredient reservoirs using the accumulator chamber.

Pneumatic system for fluid mixture dispensing device

In some embodiments of a fluid dispensing system: (1) two or more mixing channels are fluidly connected to (a) a mixing chamber fluidly connected to a dispenser, (b) a particular two or more solvent reservoirs, and (c) a respective one or more ingredient reservoirs, wherein each of the ingredient reservoirs is configured to dispense into a respective one of the mixing channels; and (2) a controller is programmed to receive a request for a fluid mixture, and, in response control the system to: mix, in the mixing channels to form an intermediate fluid mixture, a respective predetermined amount of solvent from each of the particular solvent reservoirs and a respective predetermined amount of the ingredients from some of the ingredient reservoirs; flow, to the mixing chamber and then to the dispenser, the intermediate fluid mixture; and dispense the requested fluid mixture (including the intermediate fluid mixture) via the dispenser.

Systems and methods for dispensing fluid mixtures

The present invention provides for assessing biological samples for developmental viability utilising microscopy by contemporaneously capturing bright field and dark field images of a biological sample within a time lapse measurement interval.

Method and apparatus for microscopy

Ingredient dispensing systems and methods are disclosed. A disclosed system includes an ingredient reservoir and an electromechanical valve configured so that, when the electromechanical valve is activated, an ingredient is dispensed from the ingredient reservoir. The disclosed system also includes a current sensor configured to measure a current draw of the electromechanical valve. The disclosed system also includes a controller programmed to sample the current draw from the current sensor and to detect a dispense error of the electromechanical valve based on the sampled current draw.

Valve current error detection for fluid mixture dispensing device

At least some embodiments of the technology are directed to an automated slide processing apparatus configured to apply at least one reagent to a specimen carried by a microscope slide. The slide processing station can include a support element with a support surface, at least one vacuum port, and a sealing member having a non-round shape. In an uncompressed state, the sealing member can extend upwardly beyond the support surface. In a compressed state, the sealing member can be configured to maintain an airtight seal with a backside of the microscope slide as the microscope slide is pulled against the support surface by a vacuum drawn via the at least one vacuum port.

A specimen processing system is capable of processing specimens carried on slides. The specimen processing system can sequentially deliver slides and opposables to specimen processing stations. The specimen processing stations can use the opposables to apply a series of liquids to the specimens. The applied liquid can be moved along the slide using capillary action while the specimen processing stations control the processing temperatures.

Specimen processing systems and methods for aligning slides

The present invention relates to the field of testing and evaluation of biological samples and provides an apparatus for cultured samples including at least one independently accessible module adapted for incubating at least one of a number of samples wherein the at least one module is operatively associated with a light source and a movable optical inspection means adapted for motion about a viewing axis through the module to enable a sweeping of viewing area. The invention also provides a method of assessing cultured samples for viability, including the steps of: disposing biological samples in a substantially elliptical arrangement within a culturing chamber of an independently accessible module and imaging individual samples of the substantially elliptical arrangement with optical inspection means driven within an X-Y plane that is normal to a viewing axis through the module to obtain time lapse measurement of development of individual samples.

Apparatus, method, and system for cultured sample development monitoring

Processing containers include a first member having a substantially rigid body with a plurality of regions defining spaced apart workstations and a flexible barrier member sealably attached to the first member to define a closed chamber over the plurality of workstations. The flexible barrier is substantially impermeable and includes or is a manipulation tool that is sealably attached to the barrier. The manipulation tool has a first internal interface that resides in the closed chamber under the flexible barrier and a second external interface that resides outside the closed chamber. The processing containers are particularly suitable for automated processing of nucleic acids and other samples. The manipulation tool can cooperate with or include a pipette head. When the barrier is sealed, the barrier separates the contents of the container from a robotic arm or other manipulation device.

Methods of processing samples

Growing community of inventors

Victoria, Australia

Simon Jonathon Spence