Merck Patent Gmbh

Simon Geissler

Martina Victoria Schmidt

Markus Weigandt

Andrea Hanefeld

Michael Lange

Stefan Schiller

Peter Langguth

Holger Kubas

Martina Schmidt

Meike Harms

Martina Jeschke

Patrizia Boniforte

A pharmaceutical formulation has (S)-[2-chloro-4-fluoro-5-(7-morpholin-4-yl-quinazolin-4-yl)phenyl]-(6-methoxy-pyridazin-3-yl)methanol or pharmaceutically acceptable salt thereof.

Pharmaceutical formulation

The present invention relates to a solid pharmaceutical preparation of 3-Fluoro-4-[7-methoxy-3-methyl-8-(1-methyl-1H-pyrazol-4-yl)-2-oxo-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl]-benzonitrile, a method of making same, and medical uses thereof.

Pharmaceutical preparation

The present invention relates to a lyophilized nanoemulsion comprising a lipophilic phase and one or more sucrose fatty acid esters, to the nanoemulsion which can be prepared from the lyophilized nanoemulsion by redispersion, and to a process for the preparation of the lyophilized nanoemulsion.

Lyophilized nanoemulsion

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Bad Homburg, Germany

Simon Geissler