Anadys Pharmaceuticals, Inc.

Simon Fletcher

James Richard Appleman

Joyce Tan

The invention relates to a method for treating disease such as viral infections, tumors, and cancers, comprising administering a TLR7 agonist or TLR7 agonist prodrug according to a cyclical dosing schedule having a dosing period and a resting period. For example, the method encompasses treating disease with: 5-amino-3-(2'-O-acetyl-3&#x2032;-deoxy-&#x3b2;-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one Tosylateaccording to a dosing schedule of every-other-day or a dosing schedule of three consecutive days of dosing followed by four consecutive days of not dosing.

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San Diego, CA, United States of America

Simon Fletcher