Roche Molecular Systems, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Sim-Jasmine Truong

Wei-min Liu

Yan Li

Xiaoju Max Ma

Xiaoying Chen

Xiaoju (Max) Ma

Wei-Min Liu

Xiaoju (max) Ma

Accurate and fast mapping of sequencing reads obtained from a targeted sequencing procedure can be provided. Once a target region is selected, alternate regions of the genome that are sufficiently similar to the target region can be identified. If a sequencing read is more similar to the target region than to an alternate region, then the read can be determined as aligning to the target region. The reads aligning to the target region can then be analyzed to determine whether a mutation exists in the target region. Accordingly, a sequencing read can be compared to the target region and the corresponding alternate regions, and not to the entire genome, thereby providing computational efficiency.

Accurate and fast mapping of reads to genome

Growing community of inventors

Union City, CA, United States of America

Sim-Jasmine Truong