The United States of America, As Represented by the Secretary, Department of Health and Human Services

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

Hadasit Medical Research Services and Development Ltd.

Silvio Gutkind

Michael M Friedman

Doron Steinberg

Zakhar Nudelman

Irith Gati

Rakefet Czernimski

Rakefet Czerninski

The present invention discloses a method of treating a head and neck cancer or preventing the development of pre-malignant lesions to this cancer, by administering locally to the oral cavity, a sustained release drug delivery system comprising a drug for the treatment of this cancer or for the prevention of said lesions, and at least one polymer, such that said system is attached to a surface in the oral cavity and remains attached thereto for at least 1 hour, accompanied by release of the drug and maintaining an effective therapeutic concentration thereof in the cavity, for at least 1 hour. Further are disclosed a sustained release drug delivery system and a liquid precursor varnish composition to this system.

Sustained release delivery systems for the prevention and treatment of head and neck cancers

Growing community of inventors

Potomac, MD, United States of America

Silvio Gutkind