Soligenix, Inc.

Heraeus Deutschland Gmbh & Co Kg

W.c. Heraeus Gmbh

Context Biopharma Inc.

Dequssa Akteingesellschaft

Arumugham, Rasappa

Schaber, Christopher

Werner, Silvia

Rauter, Holger

Silvia Werner

Holger Rauter

Rasappa Gounder Arumugham

Christopher Schaber

Karlheinz Drauz

Hans-Peter Krimmer

Stefan Proniuk

Holger Bindernagel

Ulf Tilstam

Friedrich Wissmann

Steffen Jost

Christian Brandes

Stefanie Schmengler

Raimund Seliger

Rasappa Arumugham

Improved systems and methods for producing synthetic hypericin at high volume and high purity. In particular, systems and methods of preparing a purified synthetic hypericin resulting from irradiation, wherein the irradiation step is performed in a continuous flow micro-reactor. The process of manufacturing purified synthetic hypericin results in the synthetic yield of 30-100% of the dry product.

Systems and methods for producing synthetic hypericin

Methods and systems for making intermediates in the synthesis of onapristone are provided. Aspects include the photoconversion of onapristone synthesis intermediates using a narrow band frequency light source.

Methods of making onapristone intermediates

Improved systems and methods for producing synthetic hypericin at high volume and high purity.

The present invention describes the dihydrate of 1,2-cyclohexanediaminplatinum(II)-bis-(4-methylbenzenesulfonate), a method for producing 1,2-cyclohexanediaminplatinum(II)-bis-(4-methylbenzenesulfonate) and the hydrates thereof, and the use of 1,2-cyclohexanediaminplatinum(II)-bis-(4-methylbenzenesulfonate) and of the hydrates thereof.

1,2-cyclohexanediaminplatinum(II)-bis-(4-methylbenzenesulfonate) and the hydrates thereof

Methods for manufacturing 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxy-camptothecin are described comprising

Methods for preparing Irinotecan

Alkaline earth metal salts of 2-pyrrolidone-5-carboxylic acid (pyroglutamic acid) are prepared by heating the corresponding alkaline earth metal salt of glutaminic acid in the solid state to a temperature in a range of 120.degree. C. to 250.degree. C. until the water liberated by the intramolecular condensation (cyclocondensation) has been completely eliminated.

Method of preparing alkaline earth metal salts of

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Kahl, Germany

Silvia Werner