Abiogen Pharma S.p.a.

Silvia Trasciatti

Sergio Rosini

Fabio Neggiani

Maria Luisa Nolli

Luigi Cavenaghi

Nadia De Bernardi

The use of cholecalciferol is described as an active agent or adjuvant in muscle regeneration and in the protection of muscle tissue in subjects suffering from muscular dystrophies. Also described are pharmaceutical compositions or food supplements including cholecalciferol and suitable excipients for use in the regeneration and protection of muscle tissue in subjects suffering from muscular dystrophies.

Use of cholecalciferol as adjuvant in the treatment of muscular dystrophies

The present invention relates to a composition for use in the treatment of osteoarthritis (OA), wherein said composition comprises from 5 to 40 mg of sodium chlodronate, or an equivalent amount of chlodronic acid, or other pharmaceutically acceptable salts thereof, and wherein said composition is administered intra-articularly in a unitary dosage form once monthly, once biweekly or once weekly. Single-dose medicaments and kits comprising them are also described.

Method for the treatment of osteoarthritis

Disclosed are pharmaceutical compositions containing clodronic acid and hyaluronic acid or their salts as active constituents, mixed with suitable vehicles.

Pharmaceutical formulation for the treatment of osteoarthritis containing clodronic acid and hyaluronic acid

The present invention refers to a procedure for the large-scale amplification of human lymphocytic cell lines for therapeutic use, consisting of a homogeneous culture system. The claimed invention also refers to the production of therapeutic doses of lymphocytic cells cultured homogeneously.

Procedure for the large-scale T-lymphocytes culture in a homogeneous system

Catalytic monoclonal antibodies (abzymes) with selective protease activity in the pathologies characterized by the presence of plaques and fibrillar aggregates with protein component; methods for the preparation thereof and the use thereof as medicaments in the treatment of pathologies such as Alzheimer's disease, amyloidosis, atherosclerosis, prions diseases.

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Madonna Dell'Acqua-San Giuliano Terme, Italy

Silvia Trasciatti