Baxter Aktiengesellschaft

Silvia Neppl

Hans-Peter Schwarz

Yendra Linnau

Ernst Hetzl

Wolfgang Sch&ouml;nhofer

H Peter Matthiessen

A method of purifying antithrombin III (AT III) from a starting material containing an AT III/heparin complex or an AT III/heparinoid complex is disclosed. First, the method comprises adsorbing the AT III/heparin complex or the AT III/heparinoid complex on an anion exchanger material. Second, the method involves separating the AT III from the adsorbed AT III/heparin complex or an AT III/heparinoid complex by elution with a buffer having a pH ranging from 8.5 to 10.5 and a conductivity between 10 and 60 mS.

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Vienna, Austria

Silvia Neppl