Northwestern University

Boston Biomedical Research Institute

The General Hospital Corporation

Massachusetts General Hospital Corporation

Sigmund A Weitzman

Jonathan C Jones

Philip J Graceffa

Stephanie Stahl

A method of growing epithelial cells by contacting the cells with the extracellular matrix deposited or secreted by human MCF-10A mammary epithelial cells. The MCF-10A matrix stimulates cell attachment and hemidesmosome formation in epithelial cells contacted therewith. The invention also encompasses the isolated or purified MCF-10A matrix, compositions comprising the matrix, and shaped articles coated with the matrix.

Human epithelial cell matrix and uses therefor

This invention pertains to an improved method of inhibiting peroxide-reduction catalytic activity and concomitant toxicity of asbestos and nonasbestos iron-containing silicates. These undesirable reactions can be substantially reduced or essentially eliminated by contacting these potentially harmful materials with an aqueous solution comprising a non-mutagenic non-toxic iron chelating agent, such as phytic acid, diethylenetriamine pentaacetic acid (DTPA) or derivatives of these.

Treatment of asbestos and silicates to reduce their toxicity

Toxicity of asbestos is reduced by treating it with non-mutagenic non-toxic hydroxamic acid iron-chelating agents.

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Winnetka, IL, United States of America

Sigmund A Weitzman