Hoechst Aktiengesellschaft

Aventis Research & Technologies Gmbh & Co Kg

Wintershall Aktiengesellschaft

Siegmund Lang

Fritz Wagner

Dieter Wullbrandt

Andreas Brakemeier

Walter Lindorfer

Carlo Giani

Walther Schulz

Kai-Udo Sewe

Hans-Jurgen Hofmann

Egbert Ristau

Andreas Seiffert-St&ouml;ricko

Zu-yi Li

The invention relates to sophoroselipids of formula (I) wherein R represents H, &mdash;CH CH , &mdash;CH CH CH , n is an integer number from 2 to 27, R and R represent, independently from each other, H or a group of formula (II), and R represents H or &mdash;OH. The invention also relates to a method for producing sophoroselipids of formula (I) wherein R , R , R and n have the aforementioned meanings and R represents &mdash;CH , &mdash;CH CH or &mdash;CH CH CH . According to this method, a yeast capable of secreting a sophoroselipid in the form of a lactone in the culture excess, is fermented in a culture medium containing a glycerin. a succinate, a mono-, di- and/or tri-saccharide and a lipid precursor, said sophoroslipid being then isolated from the culture solution. The inventive method is characterised in that the lipid precursor contains one or more 3-alkanols, 4-alkanols or an alkanone with a chain length from 6 to 30 carbon atoms or mixtures of said alkanoistalkanone. Furthermore, according to a variant of the aforementioned method for producing sophoroselipids of formula (I), wherein R , R , R and n have the meanings aforementioned and R represents &mdash;CH , &mdash;CH CH or &mdash;CH CH CH , the culture medium is maintained during fermentation under a reduced oxygen concentration. The new sophoroselipids may be used, e.g., as surfactants, cosmetics, disinfecting agents or pharmaceutical products.

Sophoroselipids, method for their production and use

The present invention relates to glucose- and sophorose-lipids of the formula I ##STR1## in which R.sup.4 is --OH or a group of the formula II, ##STR2## n is an integer from 2 to 26, R.sup.1 and R.sup.2 are, independently of one another, H or ##STR3## R.sup.3 is H or --OH in the case where R.sup.4 is --OH, and is H or --OH or a group of the formula III, ##STR4## in the case where R.sup.4 is a group of the formula II, to a process for obtaining them by fermentation, and to their use as surfactants.

Glucose- and sophorose-lipids, a process for their preparation and their

Anionic, surface-active trehalose lipids, in which different organic acids are bound to a trehalose molecule by an ester linkage, are prepared by aerobically cultivating trehalose-producing microorganisms, capable of assimilating hydrocarbons, under growth-limiting conditions, but without limiting the oxygen.

Trehalose lipid tetraesters

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Braunschweig, Germany

Siegmund Lang