Henkel Kommanditgesellschaft Auf Aktien

Henkel Kgaa

Henkel Kommanditgesellschaft

Henkel Kommanditgesellschaft (kgaa)

Siegfried Wallat

Hinrich Moeller

Hinrich Moller

Friedhelm Bartnik

Karl Giede

Horst Hoffkes

Wolfgang Pittermann

Hinrich M/o/ Ller

Novel alkyl aryl ether derivatives corresponding to the formula: ##STR1## in which R.sup.1 is a C.sub.8 -C.sub.20 alkyl group with one or more branches, E is a group --CH.sub.2 --CH.sub.2 -- or --CH.dbd.CH-- and R.sup.2 is a C.sub.1 -C.sub.4 alkyl group, a C.sub.2 -C.sub.4 hydroxyalkyl group, an alkoxyalkyl group containing 1 to 4 C atoms in the alkoxy group and 2 to 4 C atoms in the alkyl group, hydrogen or a salt-forming cation, are highly effective sebosuppressive agents in cosmetic or pharmaceutical preparations for topical application to the hair and to the skin.

Novel sebosuppressive compounds and preparations

Sebosuppressive compositions comprising a cosmetically- and pharmaceutically-acceptable carrier and an antiseborrheic agent consisting essentially of a 4-alkoxy- or 4-(4-alkylbenzyloxy)-benzoic acid and a purine compound corresponding to the formula: ##STR1## or the purine 1,3,7,9-tetramethyluric acid; or a physiologically-acceptable salt thereof. The antiseborrheic action of the 4-alkoxy- or 4-(4-alkylbenzyloxy)-benzoic acids is potentiated by the purine compounds. Preferred purine compounds are theophylline, theobromine and caffeine.

Sebosuppressive compositions and method for suppressing sebaceous gland

A cosmetic preparation for the treatment of seborrhea containing an antiseborrheically effective amount of a p-alkoxy or p-alkylbenzyloxy benzoic acid ester having the formula ##STR1## wherein R.sup.1 is (i) a branched alkyl group having from 6 to 18 carbon atoms,

Sebosuppressive benzoic acid ester derivatives and cosmetic preparations

A cosmetic preparation for the treatment of seborrhea containing an antiseborrheically effective amount of a p-alkoxy or p-alkybenzyloxy benzoic acid or salt thereof having the formula ##STR1## wherein R is either an alkyl group having from 6 to 18 carbon atoms, or an alkybenzyl group wherein the alkyl moiety has from 3 to 9 carbon atoms, and X is a member selected from the group consisting of hydrogen, an alkali metal, an alkaline earth metal and ammonium, and further containing conventional vehicles and additives; the process for reducing mammalian sebum production by using the above cosmetic preparation; and certain p-alkoxy and p-alkylbenzyloxy benzoic acids or salts thereof of the above formula.

Sebosuppressive cosmetic preparations containing alkoxy or

Substituted benzyl alcohols and substituted phenyl ethanols which are novel and the use of these and related compounds known per se, as sebosuppressives.

Sebosuppressive preparations containing alkoxyaryl alkanols

Sebosuppressive cosmetic preparations containing benzyl alcohol derivatives which are substituted on the benzene ring by alkyl, aryl, alkyloxymethyl radicals or by a fused aromatic ring, and methods for their use.

Sebosuppressive preparations containing benzyl alcohol derivatives

This invention relates to a topical cosmetic preparation for treating oily hair or seborrhea which contains a sebosuppressively effective amount of at least one 4-aryl-4-oxo-but-2-enoic acid derivative.

Sebosuppressive cosmetic preparations containing aryloxobutenoic acid

Arene-carboxylic acid derivatives as antiseborrheic additives for

Method of using certain aryl-mercapto-lower-alkanamides as

A topical cosmetic preparation for the treatment of seborrhea containing a sebosuppressively effective amount of at least one alkoxybenzoic acid ester having the formula ##STR1## wherein R.sup.1 represents a C.sub.6-20 -n-alkyl and R.sup.2 is a member selected from the group consisting of --CH.sub.2 OR.sup.3, --C.sub.2 H.sub.4 OR.sup.3, --CH.sub.2 OC.sub.2 H.sub.4 OR.sup.3, --CH.sub.2 OH, --C.sub.2 H.sub.4 OH, --CH(CH.sub.3)OH, --CH.sub.2 NR.sup.3 R.sup.4, --C.sub.2 H.sub.4 NR.sup.3 R.sup.4, --CO.sub.2 R.sup.3 and --CH.sub.2 CO.sub.2 R.sup.3, wherein R.sup.3 and R.sup.4 are C.sub.1-4 -alkyl, as an antiseborrheic, and further containing conventional vehicles and additives for topical application; as well as the process for reducing sebaceous cell sebum production in a mammal in need thereof using the above cosmetic preparation; and the alkoxybenzoic acid esters of the above formula.

Sebosuppressive topical cosmetic preparations containing alkoxybenzoic

This invention relates to a topical cosmetic preparation for treating oily hair or seborrhea which contains a sebosuppressively effective amount of at least one long-chain alkanol and at least one antioxidant.

Sebosuppressive cosmetic preparations containing long-chained _alkanols

This invention relates to topical cosmetic preparations. More particularly, this invention relates to a topical cosmetic preparation for the treatment of oily hair and seborrheic skin which comprises an effective amount of at least one compound of the formula ##STR1## wherein R.sub.1, R.sub.2, and R.sub.3, any of which may be the same or different, each represent hydrogen, hydroxyl, or --OR.sub.4, where R.sub.4 is an alkyl of from 1 to 6 carbon atoms or a substituted or unsubstituted benzyl, or two of the groups R.sub.1, R.sub.2, and R.sub.3 represent methylenedioxy; X is a substituted or unsubstituted alkylene of from 1 to 3 carbon atoms; and Y is --COOH, --CN, --CONR.sub.5 R.sub.6, or --COOR.sub.7, where R.sub.5 and R.sub.6 each represent hydrogen, alkyl of from 1 to 6 carbon atoms, or substituted or unsubstituted aryl, or aralkyl, or together with the nitrogen atom R.sub.5 and R.sub.6 represent a heterocycle, and R.sub.7 is an alkyl of from 1 to 6 carbon atoms or a substituted or unsubstituted aralkyl.

Topical cosmetic preparations for the treatment of oily hair and

A topical cosmetic preparation for the treatment of seborrhea containing an antiseborrheically effective amount of at least one compound having the formula ##STR1## wherein Ar represents a member selected from the group consisting of phenyl, phenyl substituted with at least one group selected from the group consisting of alkyl having from 1 to 4 carbon atoms, alkoxy having from 1 to 4 carbon atoms, hydroxy and halo, naphthyl and heteroaromatic radical having from 4 to 5 carbon atoms in the cycle, and R represents a member selected from the group consisting of hydrogen, alkyl having from 1 to 4 carbon atoms, alkanoyl having from 1 to 4 carbon atoms, aryl and arylcarbonyl, where aryl has the same meaning as Ar, as an antiseborrheic, and further containing conventional vehicles and additives. The invention also relates to the process for reducing sebaceous cell sebum production employing said topical cosmetic preparation.

Growing community of inventors

Monheim, Germany

Siegfried Wallat