Roche Diagnostics Operations, Inc.

Roche Molecular Systems, Inc.

Roche Diabetes Care, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-La Roche Ag

Siegfried Dick

Markus Fischer

Stephen Gordon Will

Martin Frank

Werner Finke

Andreas Trapp

Alexander Schmelzer

Peter Stubenbord

Günter Schmidt

Josef K Röper

Gunter Schmidt

Josef K Roper

A multi-layer plasma separation card comprising (a) a first layer including a sample receiving member comprising (i) a top planar surface for applying or receiving a blood sample, said sample receiving portion being adapted to permit contact of said blood sample with a separating member; and (ii) a bottom planar surface being adapted to contact said separating member, (b) a second layer including at least three separating members, each separating member being adapted to permit the passage of plasma to an absorptive member and comprising (i) a top planar surface for receiving said blood sample; and (ii) a bottom planar shield-shaped surface being adapted to contact said absorptive member, and (c) a third layer including at least two absorptive members for absorbing plasma from the bottom planar surface of each corresponding separating member and a backing member arranged in a manner to support said absorptive members, each absorptive member comprising a removable absorptive element having a top planar surface being adapted to contact said bottom planar surface of the separating member, said absorptive element is detachable fixed to the third layer.

Plasma separation card

The test elements are provided that are adapted to detect at least one analyte in a sample. At least some of the test elements are provided with a defect marking which contains information about defectiveness of the test elements. The test elements include at least one radiation-sensitive material. The test elements are exposed to at least one radiation, the radiation being adapted to induce marking in the form of at least one optically detectable change in the radiation-sensitive material.

Marking method for the reject marking of test elements

A process for the production of at least one analytical device is disclosed. The analytical device comprises at least one capillary element. The process comprises providing at least one carrier layer; providing at least one spacer layer; applying the spacer layer on top of the carrier layer; providing at least one cover layer; and applying the cover layer on top of the spacer layer. The process further comprises at least one cutting step. At least one capillary channel of the capillary element is cut out from the spacer layer. The cutting step is performed by using at least two cutting tools. The cutting tools complement one another to form a contour of the capillary channel.

Process and production device for the production of at least one analytical device

Growing community of inventors

Mannheim, Germany

Siegfried Dick