Millennium Pharmaceuticals Limited

Sian Griffiths

Shomir Ghosh

Francois Soucy

Kevin Sprott

Amy M Elder

Prakash Raman

Qing Ye

The present invention provides compounds of general formula (I) or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and Rare defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR2 and accordingly are useful for the treatment of a variety of inflammatory, allergic, and autoimmune diseases, disorders, or conditions. 

Compounds useful as antagonists of CCR2

The present invention provides compounds of general formula I: or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R1 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR2 and accordingly are useful for the treatment of a variety of inflammatory, allergic, and autoimmune diseases, disorders, or conditions. 

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Westborough, MA, United States of America

Sian Griffiths