University of Utah Research Foundation

Siam Oottamasathien, Viii

Glenn D Prestwich

Wanjian Jia

Won Yong Lee

Lindsi McCoard

Described herein are methods for treating or preventing urological inflammation in a subject comprising administering to the subject an effective amount of a compound comprising a. a modified hyaluronan or a pharmaceutically acceptable salt or ester thereof, wherein said hyaluronan or its pharmaceutically acceptable salt or ester comprises at least one sulfate group and at least one primary C-6 hydroxyl position of an N-acetyl-glucosamine residue comprising an alkyl group or fluoroalkyl group; b. a partially or fully sulfated hyaluronan or the pharmaceutically acceptable salt or ester thereof, or a combination thereof.

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Salt Lake City, UT, United States of America

Siam Oottamasathien, Viii