Baylor Research Institute

Shusuke Toden

Ajay Goel

Roshni Roy

Wenhao Weng

Raju Kandimalla

Tsuyoshi Ozawa

Takatoshi Matsuyama

Dysregulated expression of microRNAs (miRNAs) has emerged as a hallmark feature in human cancers. Aspects of the disclosure relate to methods for selecting optimal therapy for a patient from several alternative treatment options. A major clinical challenge in cancer treatment is to identify the subset of patients who will benefit from a therapeutic regimen, both in metastatic and adjuvant settings. The number of anti-cancer drugs and multi-drug combinations has increased substantially in the past decade, however, treatments continue to be applied empirically using a trial-and-error approach. Here methods and compositions are provided to determine the optimal treatment option for cancer patients.

Growing community of inventors

Dallas, TX, United States of America

Shusuke Toden