Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai

Shunro Mori

Hamao Umezawa

Akira Takamatsu

Compounds having the formula ##STR1## (the meanings of R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are indicated hereinafter) exhibit suppressive activity to various immune responses and can be employed in the therapy of immunological diseases, especially autoimmune diseases. One example is 3',5'-dichloro-2,4'-diacetoxybenzanilide having the formula ##STR2## and another is 3',5'-dichloro-2,4'-dibenzoyloxyanilide having the formula ##STR3##

Pharmaceutical method for the therapy of immune diseases

Compounds having the formula ##STR1## (the meanings of R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are indicated hereinafter) exhibit suppressive activity to various immune responses and can be employed in the therapy of immunological diseases, especially autoimmune diseases. One example is 3',5'-dichloro-2,4'-dihydroxybenzanilide having the formula ##STR2## AND ANOTHER IS 3',5'-DICHLORO-2,2'-DIHYDROXYBENZANILIDE HAVING THE FORMULA ##STR3##

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Fujisawa, Japan

Shunro Mori