Banyu Pharmaceutical Co. Ltd

Shunji Sakuraba

Akio Kanatani

Minoru Moriya

Hidekazu Takahashi

Hiroyuki Kishino

Takao Suzuki

Toshihiro Sakamoto

Makoto Jitsuoka

Hisashi Iwaasa

Sayaka Mizutani

Minoru Kameda

The present invention provides an imidazopyridine compound represented by formula (I), wherein Rand Reach independently represent a Calkyl group et al; Rand Reach independently represent a hydrogen atom, a methyl et al; Aris a divalent substituent representing a monocyclic or bicyclic, 3- to 8-membered aromatic or aliphatic heterocyclic group et al; Arrepresents an aromatic carbocyclic group, or an aromatic heterocyclic group; W represents &#x2014;(CH)et al, and m indicates an integer of from 0 to 10. This compound acts as a melanin concentrating hormone receptor antagonist, and is useful as treating agents for obesity.

Imidazopyridine compound

A compound represented by the formula [I]: [wherein Rand Rare the same or different and each represents Calkyl, Ccycloalkyl, et al; R, R, and Rare the same or different and each represents hydrogen, Calkyl, et al; X represents &#x2014;N&#x2014;, &#x2014;CH&#x2014;, et al; Yrepresents a single bond, Calkylene, et al; Yrepresents Calkylene, oxy(Calkylene), et al; Arrepresents a monocyclic aromatic carbocyclic group, monocyclic aromatic heterocyclic group, et al; and Arrepresents a 5- or 6-membered aromatic carbocyclic group, aromatic heterocyclic group, et al]. This compound functions as a melanin-concentrating hormone receptor antagonist and is useful as, e.g., a therapeutic agent for obesity, et al.

2-arylcarboxamide-nitrogenous heterocycle compound

The invention provides imidazopyridine derivatives represented by the general formula [I] [in which Rand Rmay be the same or different and stand for Calkyl or the like, Rand Rstand for hydrogen atom, methyl group or the like, W stands for mono- or bi-cyclic 3- to 8-membered aromatic or aliphatic heterocycle or the like, and Ar stands for optionally substituted aromatic heterocycle or the like]. These compounds act as melanin-concentrating hormone receptor antagonist and are useful as medicines for central nervous system disorders, cardiovascular system disorders and metabolic disorders.

Imidazopyridine derivatives

Growing community of inventors

Tsukuba, Japan

Shunji Sakuraba