Sumitomo Chemical Company, Limited

Shun Inokuma

Takeshi Yamahara

Junki Katsube

Takashi Deguchi

Akihiko Sugie

Kenichi Hirose

Shin Tanaka

Tooru Tokumaru

Hiromi Shimomura

Yoshihiro Watanabe

Shinji Nakamura

A compound of the formula: ##STR1## wherein A.sub.1 is a single bond or a C.sub.1 -C.sub.5 alkylene group bonding at the 2-, 2'- or 3-position, A.sub.2 is a C.sub.1 -C.sub.3 alkylene group, A.sub.3 is a C.sub.1 -C.sub.4 alkylene group, X is --O-- or --SO.sub.n -- and B is a carboxy group, a C.sub.2 -C.sub.5 alkoxycarbonyl group, a cyano group, an amino group of the formula: ##STR2## or a carbamoyl group of the formula: ##STR3## which is useful as an antiviral agent with no side effect.

Tricyclic cage compounds, their synthesis and use as antiviral agents

A process for preparing acid amides by hydration of the corresponding nitrile compounds with water in the presence of a catalyst, characterized in that the catalyst is the one prepared by treating a vanadate with a cuprous salt or with at least two of metallic copper, a cuprous salt and a cupric salt.

Process for preparing acid amides

.alpha.-Amino acids are prepared by catalytically hydrolyzing a hydantoin compound of the formula, ##STR1## wherein R.sub.1 and R.sub.2 are individually hydrogen or an unsubstituted or substituted alkyl, cycloalkyl, alkenyl, aryl or aralkyl group, in the presence of imidazole or a derivative thereof.

Production of alpha-amino acids

The acid amides are produced by a process comprising hydrating a nitrile compound in the presence of a copper-containing polymer having basic nitrogenous groups in the polymer chain or linked with the polymer chain as a catalyst.

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Takatsuki, Japan

Shun Inokuma