Nof Corporation

Kyowa Medex Co., Ltd.

Tfb, Inc.

Shujiro Sakaki

Kenshiro Shuto

Hiroshi Kurosawa

Satoshi Yamada

Ken Suzuki

Nobuyuki Sakamoto

Yasumi Koinuma

Shinji Tanaka

Motohiro Mitani

Kayoko Shigenobu

Mamoru Tsuchida

Yoshihiro Ashihara

Mitsuo Isomura

The invention relates to a vessel for embryoid formation used for forming embryoid bodies from ES cells easily without complicated technique, and to a method for forming embryoid bodies easily and efficiently using the vessel. The method includes the steps of (A) providing a vessel for embryoid formation having a coating layer formed from a compound having a particular PC-like group on a vessel surface defining a region for floating culture of ES cells, and (B) floating culturing ES cells in the vessel to form embryoid bodies.

Method for forming embryoid bodies

The present invention relates to an inhibitor capable of increasing accuracy of the reaction in hybridization, and inhibiting nonspecific hybridization, a clinical diagnostic reagent, and a method of clinical analysis whereby nonspecific hybridization in clinical analysis is inhibited, and a target nucleic substance is detected easily with high accuracy. The inhibitor and the clinical diagnostic reagent contains polymer (H) having a nonspecific hybridization inhibitory action. The polymer has in its molecule at least one of carboxyl and sulfone groups, and phosphorylcholine-like groups, and has a weight average molecular weight of 1000 to 5000000. The method of clinical analysis includes contacting a sample with a test agent capable of hybridizing with a specific nucleic substance in the presence of the inhibitor.

Nonspecific hybridization inhibitors, clinical examination reagents and clinical examination method

Container for germ layer formation and method of forming germ layer

The present invention provides an agglutination immunoassay, wherein the agglutination of insoluble carrier particles such as latex are stabilized and uniformized to give good reproducibility, and a reagent therefor. In the agglutination immunoassay which comprises allowing an antigenic substance in a sample to bind to insoluble carrier particles carrying substantially neither antigens nor antibodies thereon, and allowing an antibody or an antibody complex which reacts specifically to the antigenic substance to bind to the antigenic substance to give a selective agglutination of the insoluble carrier particles, a homopolymer prepared by polymerization of a monomer such as 2-methacryloyloxyethyl phosphorylcholine having a phosphorylcholine group and a vinyl group, or a copolymer prepared by polymerization of a monomer having a phosphorylcholine group and a vinyl group, with a monomer having a vinyl group such as n-butyl methacrylate is used.

Highly reproducible agglutination immunoassay method and reagents

A composition for hydrogels which comprises (A1) a copolymer which comprises 25 to 97 mol % of unit (a) derived from a compound represented by formula (1) and 3 to 75 mol % of unit (b) derived from a monomer represented by formula (2) and is soluble in aqueous media and (B) a polymer which has hydrophilic groups such as hydroxyl or carboxyl groups and is soluble in aqueous media; and a hydrogel comprising the composition. (X represents a divalent organic residue; Y represents alkyleneoxy, etc.; Z, R, R, R, R, and Leach represents hydrogen, etc.; and Lrepresents &#x2014;CH&#x2014;, etc.)

Composition for hydrogel, hydrogel and use thereof

A polymerized product of protein, comprising a polymer of one or more protein-containing monomers represented by the general formula

Polymerized product of protein and process for producing it

Growing community of inventors

Tsukuba, Japan

Shujiro Sakaki