Lion Corporation

Shuji Sasaki

Tatsuo Kiyoshige

Yoji Yamazaki

Tsuneaki Nakamura

A composition for oral application comprises a nonspecific .gamma.-globulin as an effective ingredient for preventing Bacteroides gingivalis from colonizing in the mouth.

Composition for oral application

A reagent for the enumeration of oral gram-negative bacteria, such as Bacteriodes melaninogenicus, Capnocytophaga sp. and Eikenelia corrodens, by an indirect fluorescent antibody method is provided which utilizes an unlabelled antiserum to oral gram-negative bacteria and a fluorescent conjugated antibody obtained by immunizing an animal of a different species than the antiserum with .gamma.-globulin of an animal of the same species as the antiserum. A sample containing oral gram-negative bacteria to be enumerated is treated with the antiserum and the reaction product obtained is then treated with the fluorescent conjugated antibody to enumerate the bacteria in the sample by observing under a fluorescent microscope.

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Odawara, Japan

Shuji Sasaki