Nestec S.a.

Societe Des Produits Nestle S.a.

Shui-Long Wang

Sharat Singh

Nicholas Chi-Kwan Ling

Linda Ohrmund

Fred Princen

Steven Lockton

Stefan Westin

The present invention provides assays for detecting and measuring the presence or level of anti-TNF&#x3b1; drug therapeutics and autoantibodies in a sample. The present invention is useful for optimizing therapy and monitoring patients receiving anti-TNF&#x3b1; drug therapeutics to detect the presence or level of autoantibodies (e.g., HACA and/or HAHA) against the drug.

Assays for the detection of anti-TNF drugs and autoantibodies

The present invention provides methods for aiding in the diagnosis of irritable bowel syndrome (IBS) in an individual. In particular, the present invention is useful for determining whether a sample from an individual is an IBS sample or a healthy control sample using a statistical algorithm. Thus, the present invention provides an accurate diagnostic prediction of IBS and is useful for guiding treatment decisions.

Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for IBS

The present invention provides devices and methods for aiding in the diagnosis of Crohn's disease. The devices and methods accurately identify whether a sample from an individual is associated with inflammatory bowel disease (IBD) or a clinical subtype thereof such as Crohn's disease (CD). The present invention is useful for determining whether a sample from an individual is an IBD sample, or differentiating between CD and ulcerative colitis (UC). Thus, the present invention provides an accurate diagnostic prediction of IBD or a clinical subtype thereof and prognostic information useful for guiding treatment decisions.

Assays and methods for the detection of Crohn's disease

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San Diego, CA, United States of America

Shui-Long Wang