Medshine Discovery Inc.

Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Guangdong Raynovent Biotech Co., Ltd.

Other

Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd.

Cspc Zhongqi Pharmaceutical Technology (shijiazhuang) Co., Ltd.

Shandong Danhong Pharmaceutical Co., Ltd.

Qilu Pharmaceutical Co., Ltd.

Sichuan University

Jiangsu Aosaikang Pharmaceutical Co., Ltd.

Yangtze River Pharmaceutical Group Co., Ltd.

Shanghai Haiyan Pharmaceutical Technology Co., Ltd.

Shandong Luye Pharmaceutical Co., Ltd.

Jiangsu Kanion Pharmaceutical Co., Ltd.

Nanjing Sanhome Pharmaceutical Co., Ltd.

Shuhui Chen

Jian Li

Charles Z Ding

Guoping Hu

Haiying He

Lihong Hu

Lingyun Wu

Chengde Wu

Jie Li

Wenyuan Qian

Peng Li

Kevin X Chen

Chaofeng Long

Xiaoxin Chen

Zhengxia Chen

Tao Yu

Fang Liu

Yunfu Luo

Wentao Wu

Chundao Yang

Jianfei Wang

Hao Wu

Fei Sun

Zhigan Jiang

Zhi Luo

Zhuowei Liu

Zhen Gong

Peng Zhang

Yong Wang

Jian Xiong

Xiaolin Li

Bin Chen

Zhaozhong Ding

Fei Wang

Kai Zhou

Zheng Wang

Yuan Chen

Xiquan Zhang

Xuanjia Peng

Weidong Li

Chen Zhang

Xing Liu

Lei Zhang

Wei Luo

Cheng Li

Ling Yang

Tie-Lin Wang

Yuquan Wei

Yong Xu

Lie Li

Shilan Liu

Ning Li

Weihua Shi

Wei Huang

Wei Wang

Xiao Xun Zhang

Jing Wang

Cong Wang

Hui Liu

Jun Yin

Hongwei Li

Feng Gao

Hongjiang Xu

Tao Feng

Jing Zhang

Zhiqiang Liu

Dahai Wang

Jun Lin

Bo Gao

Ting Wang

Yan Wang

Jian Wang

Yong Liang Liu

Ming Zhang

Yi Bu Li

Bin Liu

Yi Chen

Yang Zhang

Jiong Lan

Chun Sing Li

Lu Zhang

Feng Guo

Wei Wei

Wei Gu

Kun Peng Wang

Jun Yu

Xin Tian

Rui Zhao

Ling Liu

Long Zhang

Jie Gandalf Yan

Jun Zhao

Xiao Liu

Xu Zeng

Hui Zhou

Aiming Zhang

A crystal form of a pyridinylphenyl compound and a preparation method therefor. Use of the crystal form in the preparation of a medicament of treating related diseases is also comprised.

Crystal form of pyridinylphenyl compound and preparation method therefor

Disclosed are a series of compounds having pyridine structures or pharmaceutically acceptable salts thereof, and an application thereof in the preparation of drugs for the treatment of related diseases. Specifically, disclosed is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof.

Pyridine derivative and application thereof

The present disclosure discloses a class of macrocyclic derivatives, and specifically discloses a compound shown in formula (VI), a stereoisomer thereof, and a pharmaceutically acceptable salt thereof.

Macrocyclic derivative and use thereof

Provided are a class of multi-targeted inhibitors of IRAK4 and BTK, and the use thereof in preparing a drug for treating IRAK4- and BTK-related diseases. The present invention specifically relates to the compounds represented by formula (II), isomers thereof or pharmaceutically acceptable salts thereof.

Oxazole compound as multi-targeted inhibitor of IRAK4 and BTK

Disclosed is a fluoropyrrolopyridine compound, and specifically disclosed is a compound represented by formula (II), an isomer or a pharmaceutically acceptable salt thereof.

Fluoropyrrolopyridine compound and application thereof

Provided is an isochroman compound represented by formula (I), or a pharmaceutically acceptable salt thereof, which is used as an aldo-keto reductase (AKR1C3) inhibitor for the treatment of liver cancer.

Isochroman compound

Disclosed in the present invention is a series of dimethylsulfoximine derivatives, and specifically disclosed are a compound represented by formula (II) and a pharmaceutically acceptable salt thereof.

Dimethylsulfoximine derivative

Compounds as SGLT2/DPP4 dual inhibitors, and application in preparation of medicines as the SGLT2/DPP4 dual inhibitors. A compound represented by formula (I), and an isomer or pharmaceutically acceptable salt thereof are specifically involved.

SGLT2/DPP4 inhibitor and application thereof

A class of KRAS G12C mutant protein inhibitors, specifically disclosing the compound shown in formula (I), and an isomer and a pharmaceutically acceptable salt thereof.

Seven-membered heterocyclic derivative acting as KRAS G12C mutant protein inhibitor

A novel indazole compound, a preparation method therefor, and use thereof in the preparation of drugs for treating related diseases. Specifically disclosed are a compound of formula (II) and a pharmaceutically acceptable salt thereof.

Indazole-fused cyclic compound

Disclosed are a series of benzopyrimidine compounds and a use thereof, and specifically disclosed are compounds represented by formula (II) and pharmaceutically acceptable salts thereof.

Benzopyrimidine compounds and use thereof

A class of salt forms and crystal forms of a tetrahydrocyclohepta indazole compound and a preparation method therefor. Specifically disclosed is the uses of the salt form and crystal form of the compound of formula (I) in the preparation of a drug for treating related diseases.

Salt form and crystal form of tetrahydrocyclohepta indazole compound

Disclosed are the solid form, crystalline form, crystal form A of a compound of formula (I), and a preparation method therefor, crystal form B and a preparation method therefor. Also disclosed are use of the solid form, crystalline form, crystal form A, and crystal form B in the preparation of drugs for the treatment of diseases related to FGFR.

FGFR inhibitor compound in solid form and preparation method therefor

A Spiro compound serving as an ERK inhibitor, and an application thereof in preparing a drug for treating an ERK-related disease. The present invention specifically relates to a compound represented by formula (III) or a pharmaceutically acceptable salt thereof.

Spiro compound serving as ERK inhibitor, and application thereof

FGFR and VEGFR dual inhibitors, specifically being a compound represented by formula (I) or a pharmaceutically acceptable salt.

Pyridine derivative as FGFR and VEGFR dual inhibitors

Growing community of inventors

Shanghai, China

Shuhui Chen