Shenzhen Sciencare Medical Industries Co. Ltd.

Shugui Yin

Tao Zhang

Shaowei Jia

Shiqiang Wang

Qingzhe Liu

The present invention relates to a technical field of pharmaceutical preparation, in particular to a preparation method of naltrexone implants, including the following steps: (1) dissolving naltrexone and polylactic acid in an organic solvent to form naltrexone microspheres, and drying; (2) placing the naltrexone microspheres in a heated tableting mold for tableting, and obtaining naltrexone implant tablets; (3) dissolving the polylactic acid in the organic solvent to obtain a coating solution, and placing the coating solution in a coating pool, and then immersing the naltrexone implant tablets in the coating solution, and drying in a suspended state.

Preparation method of naltrexone implants

The present invention proposes an implant coating and drying device, including a chip sorter, a slide maker, a coating pool, a tablet pipe, a tablet conveying device, and a drying device. The chip sorter is connected to the slide maker, the shape of the coating pool is a circular arc. The coating pool is filled with coating solution. The inlet of the tablet pipe is connected with the slide maker, and the outlet of the tablet pipe is connected with the drying device, the tablet conveying device is used to deliver the implant tablet within the tablet pipe. The present invention proposes an implant coating and drying device, which has the advantages of simple structure and convenient operation, and avoids the defect of the prior art that the implant tablets adhere to each other, the coating is damaged, and the release degree of the implant tablet cannot be stabilized. The present invention proposes the implant coating and drying device is suitable for mass production.

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Shenzhen, China

Shugui Yin