Northwestern University

University of Illinois

Shuai Xu

John A Rogers

Hao F Zhang

Yu Yang

Xinge Yu

Jungyup Lee

Rujie Sun

In Hwa Jung

Ha Uk Chung

Hangbo Zhao

Yonggang Huang

Jungil Choi

Chenkai Xu

Siddharth Krishnan

Philipp Gutruf

Kun Hyuck Lee

Kyeongha Kwon

Seung Yun Heo

Aurelie Hourlier-Fargette

Jong Yoon Lee

Jessica Ruth Walter

Nathaniel Zimmerman Sharpe

Edward Chenyee Tung

Yajing Li

Surabhi R Madhvapathy

Yinji Ma

Alina Rwei

Provided are apparatuses and methods for non-invasively measuring a blood pressure of a mammal subject. The apparatus includes a first sensor system and a second sensor system time-synchronized to each other and spatially separated by a pulse arrival distance L, and a microcontroller unit (MCU). The first and second sensor systems are respectively attached to first and second positions of the mammal subject for detecting first and second signals. The second position is more distal or proximal to a heart of the mammal subject than the first position. The MCU processes the output signals to determine a pulse arrival time (PAT) as a time delay Δt between detections of the first and second signals, and determines a pulse wave velocity (PWV) based on the PAT and L, where Then the MCU determines the blood pressure P from the PWV, where P is a parabolic function of the PWV.

Apparatus and method for non-invasively measuring blood pressure of mammal subject

Provided are wireless electronic devices for thermally interfacing with a biological tissue. The device may have a flexible substrate; a thermal actuator supported by said flexible substrate configured to provide a thermal input to said biological tissue; a temperature sensor supported by said flexible substrate configured to measure a temperature to determine thermal conductivity of said biological tissue; and a wireless electronic system in electronic communication with said thermal actuator and said temperature sensor, wherein said wireless electronic system is configured to provide two-way communication with an external controller. Also provided are related methods of using the electronic devices, including for cosmetic, beauty, or medical applications.

Wireless skin sensor with methods and uses

Provided are conformable light delivery devices for increasing light penetration depth and related methods. The device comprises a tissue penetrating member having a distal end and a proximal end, the tissue penetrating member configured to penetrate the tissue of the patient to be inserted into the tissue, wherein the tissue penetrating member is at least partially optically transparent along a surface of the tissue penetrating member positioned between the distal end of the tissue penetrating member and the proximal end of the tissue penetrating member to provide optical transmission of at least a portion of the light through the surface of the tissue penetrating member, thereby allowing at least the portion of the light to be delivered into the tissue of the patient when the tissue penetrating member is inserted into the tissue; and a substrate that supports the tissue penetrating member.

Devices and methods for light delivery

Provided are actuation devices, virtual reality devices formed from the actuation devices, and related virtual reality methods. The devices may comprise a plurality of spatially distributed actuators, each actuator configured for interacting with a biological skin surface; a wireless controller configured to receive operative command signals to control each of the actuators; and a wireless power system to power the actuators. Also provided are unique layouts of multiple interconnected devices to achieve large area coverage.

Epidermal virtual reality devices

An electronic system for monitoring a physical parameter includes an ADM comprising an accumulation mode sensor for measuring the physical parameter by generating electrical energy associated with the physical parameter in response to a surrounding condition, and an energy storing device coupled to the accumulation mode sensor for accumulatively storing the generated electrical energy; a power source; and an SoC coupling with the ADM and the power source, configured such that the stored electrical energy is monitored, and when the stored electrical energy is equal to or greater than a pre-defined threshold, a wake-up event is generated to trigger the SoC to operates in a run mode in which the physical parameter is wirelessly transmitted to a receiver and the stored electrical energy in the energy storing device is discharged, and then the SoC returns to a sleep mode in which a minimal power is consumed.

Ultra-low power, miniaturized electronic systems for monitoring physical parameters with wireless communication capabilities and applications of same

Provided are conformable light delivery devices for increasing light penetration depth and related methods. The device may comprise a microarray of tissue penetrating members, each member having a distal end and a proximal end, wherein the tissue penetrating members are at least partially optically transparent to provide optical transmission through a surface that extends between the distal and proximal ends of each tissue penetrating member and a substrate that supports the tissue penetrating members, wherein the substrate is optionally a flexible substrate.

Medicine dispenser

Growing community of inventors

Chicago, IL, United States of America

Shuai Xu