Lumosa Therapeutics Co., Ltd

Shanghai Lumosa Therapeutics Co., Ltd.

National Yang Ming Chiao Tung University

Shu-Wen Kuo

David Chih-Kuang Chou

Jin-Ding Huang

Yu-En Tien

Chan-Jung Li

Shin-Jr Tsai

Oscar Kuang-Sheng Lee

Meng-Hua Yen

Shin Tsai

The present invention relates to injectable, extended-release, pharmaceutical formulations comprising a nalbuphine ester prodrug homogenously dissolved in a solution comprising a pharmaceutically acceptable oil and an oil-miscible retaining solvent, as well as manufacturing processes and medical uses of the formulations. The invention further provides methods for adjusting the duration of action of the formulations by varying the ratio of the pharmaceutically acceptable oil and the oil-miscible retaining solvent.

Pharmaceutical formulations for sustained release of sebacoyl dinalbuphine ester

The present invention provides a microfluidic bio-reactor device, which comprises: a first cell culture layer; a microfluidic base, which is located on the top of the first cell culture layer; a microfluidic layer, which is located on the top of the microfluidic base and have an air-bubble removal device; a microfluidic roof, which is located on the top of the microfluidic layer; the present invention also provides a method for culturing cells by the microfluidic bio-reactor device of the present invention and the kit with a cell-loading device and present microfluidic bio-reactor device.

Microfluidic bio-reactor device

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Taipei, Taiwan

Shu-Wen Kuo