Other

Alza Corporation

Adds Pharmaceuticals LLC

Shu W Li

David E Edgren

Gurdish K Bhatti

Patrick S-l Wong

Liang-Chang Dong

Robert R Skluzacek

Si-Hong Yum

Liang C Dong

Madhavan Nair

Patrick S L Wong

Crystal Pollock-Dove

Katrina Andrea U Co

Patrick SL Wong

Methods and compositions are described whereby poorly water-soluble beneficial agents such as vitamins and co-factors are formulated into self-emulsifying formulas (SEF) and optionally sorbing the SEF into pores of porous solid particulates, or preparing supersaturated solutions (SSS) and sorbing the SSS into pores of porous solid particulates. These formulations are useful as dosage forms with oral availability.

Stabilized solubility-enhanced formulations for oral delivery

A membrane system comprising an interior wall, a fluid-permeable exterior wall surrounding the interior wall and an internal compartment defined by the membrane system, wherein fluid permeability of the interior wall is responsive to osmolarity of an osmotic core within the internal compartment are disclosed. A controlled release dosage form comprising the membrane system and a process for delivering an osmotically active formulation from an osmotic pump over an extended period of time are also disclosed.

Extended release dosage form

A composition is disclosed comprising a polymer and a surfactant in a solvent exhibiting a common solubility for the polymer and the surfactant. The composition provides a dosage form for administering a drug over time.

Pharmaceutical coating composition and method of use

A sleeping method for a participant having a foot end and a head end including 1)providing a sleeping surface having upper and lower ends, the sleeping surface inclined at least 10&#x2013;25 degrees from the upper end to the lower end, 2)providing a predetermined unit of time having successive nightly sleep periods, and 3)the participant sleeping on the sleeping surface in a head down position for at least half or other portion of the successive nightly sleep periods, the head down position comprising the participant laying down on the sleeping surface with the legs and feet of the participant disposed toward the upper end of the sleeping surface and the head end of the participant disposed toward the lower end of the sleeping surface, in which the feet end of the participant is upward relative to the head end of the participant.

Negative gravity therapeutic methods

A dosage form comprising a composition comprising a drug surrounded by an interior and an exterior wall with an exit for administering the drug to a patient; and a method of using the dosage form are disclosed for an indicated therapy.

A 10-deaza-10-formyl folate analogue is a potent inhibitor of the enzyme glycinamide ribonucleotide formyltransferase and an antitumor agent. A typical embodiment is 10-formyl-5,8,10-trideazafolic acid (FTDF).

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Mobile, AL, United States of America

Shu W Li