Kinki University

Gto LLC

Nipro Corporation

Kobayashi Pharmaceutical Co., Ltd.

Shozo Nishida

Hideki Fujita

Shunji Ishiwata

Atsushi Taga

Ayako Kita

Reiko Sugiura

Mitsuru Hasegawa

Kiyotaka Okuno

Tomoya Takeda

Masanobu Tsubaki

Satoshi Wachi

No drug has been available for treating a peripheral sensory neuropathy caused as a side effect by a drug, in particular, by an anticancer drug such as oxaliplatin. A composition for ameliorating peripheral sensory neuropathy, which is characterized by including amycelium extract, ameliorates symptoms induced by the drug such as the anticancer drug, including numbness of extremities, a pain in extremities, a reduction in deep tendon reflection, a reduction in muscle force, allodynia, hyperalgesia, impaired finger fine movement, impaired walking, stumbling, falling, impaired flexion (being difficult or impossible to sit on one's heels, sit cross-legged, sit with one's legs out to one side, sit on a chair, or the like), or paralysis of extremities.

Composition for ameliorating peripheral sensory neuropathy

Provided is an exposure-preventing cap of a novel and simple structure that, by being mounted on a vial, can more reliably inhibit leaking of drug solution to an outside when pulling out and collecting drug solution in a syringe from the vial. An exposure-preventing cap, which is mounted on a mouth of a vial sealed with a rubber stopper, wherein a puncturing hole is formed in a center part of a cap-shaped housing that is attached to a mouth of the vial, and a rubber membrane is arranged at the puncturing hole so as to form an internal space between facing surfaces of the rubber membrane and the rubber stopper. The rubber membrane has a dome shape that is convex facing the rubber stopper.

Exposure-preventing cap

A plug for a container capable of improving air-tightness and liquid-tightness is provided. A plug includes a first split piece having a cylindrical first fitting portion to be mounted on an opening portion of a container body and fitted to an opening portion space of the opening portion, an end wall which blocks one end of the first fitting portion, and a first flange portion extending outwardly in a radial direction of the first fitting portion from the other end thereof; and a second split piece having a second fitting portion which is fitted to the first fitting portion of the first split piece and forms a closed space between the end wall and the second fitting portion and a second flange portion extending outwardly in a radial direction of the second fitting portion therefrom.

Plug for container

Growing community of inventors

Higashiosaka, Japan

Shozo Nishida