Bio-Medical Sciences, Inc.

Shou-Mean Fang

Craig R Hof

A pouch for containing the gas generating means in a Time-Temperature Indicator which comprises a rate controlling film formed into a sealed pouch having contained therein a frangible ampule containing the gas generating means, said ampule being enclosed in a porous medium, said medium containing an indicator composition responsive to the gas generated by the gas generating means, so as to indicate a color change thereby making the user aware that the gas ampule has been broken.

Time-temperature integrating indicator

Temperature time integrating indicator device in which a gas generating material located at one end of the device and activated at time of use of the device is absorbed by an indicating wick extending in the device in a direction away from the gas source, which wick changes color to denote a time-temperature integral and hence the temperature history of a product, there being a gas barrier means extending along the longitudinal sides of the wick for inhibiting gas transport to insure that substantially all gas absorbed by the wick makes first contact with the wick at the end nearest the gas source thus precluding first gas contact with the wick at more remote location with consequent erroneous temperature history indication.

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Lake Hiawatha, NJ, United States of America

Shou-Mean Fang