Shionogi Company Limited

Shoji Yamane

Shoichi Naito

Tatsuya Takahashi

Junji Onoda

Yoshito Numata

Kazuhiko Maekawa

Katsutoshi Yamada

Tasuku Tsukamoto

Etsuo Nakamura

Hiroaki Aino

Sunao Imai

Akira Yamauchi

Isao Fukuda

Yasuhiko Sato

Yasunobu Yoshida

Kouhei Nishitomi

Hidekuni Yamakawa

Atsushi Morita

Provided is a humanized monoclonal antibody or an antibody fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.

Method for the treatment or prevention of a disease related to vascular endothelial lipase by administering a humanized monoclonal antibody

Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.

Method of inhibiting the enzymatic activity of vascular endothelial lipase with a monoclonal antibody

Humanized monoclonal antibody, inhibiting the enzymatic activity of vascular endothelial lipase

Monoclonal antibody, inhibiting the enzymatic activity of vascular endothelial lipase

Provided is a monoclonal antibody or a fragment thereof that selectively inhibits enzyme activity of EL and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.

Monoclonal antibody against EL which inhibits enzyme activity of EL

Provided are a monoclonal antibody capable of specifically recognizing a specific region of sAPP &#x3b2; or a fragment of said antibody and an assay method and an assay kit using the same, in order to accurately assay sAPP&#x3b2; contained in a biological sample.

Anti-sAPP&#x3b2; antibody

Growing community of inventors

Toyonaka, Japan

Shoji Yamane