Olympus Optical Company, Ltd.

Olympus Corporation

Daiichi Sankyo Company, Limited

National Cancer Center

Shoichi Saito

Hideo Shirako

Hiromichi Sakano

Kazumi Miyazi

Masaaki Sato

Tetsuya Suzuki

Hideaki Watanabe

Masao Itoh

Yutaka Masaki

Yoshiko Kagoshima

Masaaki Daigaku

Toru Wakabayashi

Tetsunori Fujisawa

Hironao Saito

Hironori Matsunaga

Kazuo Kitabayashi

Yoko Ogawara

Yohei Kiyotsuka

Koki Yamamoto

Terumasa Wada

Haruhiko;c/o Olympus Med Systems Corp Ueno

It has been found that a compound of the general formula (I) having an isoxazole skeleton has excellent inhibitory activity against mutant IDH1 protein and inhibits the production of 2-HG by this protein, while the compound is also capable of effectively inhibiting the growth of various tumors expressing the protein. In the formula, R, R, R, Y, and Z are as defined in claim

Isoxazole derivative as mutant isocitrate dehydrogenase 1 inhibitor

An optical unit includes a first unit formed by accommodating, in a first case, an optical member which receives a light beam from an object, a light amount adjustment mechanism to adjust the amount of the light beam, and a light amount adjustment actuator unit constituted by integrating first and second actuators that drive the light amount adjustment mechanism, and a second unit formed by accommodating, in a second case, a lens group which is movably arranged to obtain a predetermined object image from the light beam, and a lens driving actuator unit which is mainly constituted by a stepping motor having a stacked stator core to drive the lens group. The first and second units can detachably be coupled through a coupling unit provided between the first case and the second case.

Light amount adjustment actuator unit, stepping motor, optical unit, and electronic camera

A hydrodynamic bearing according to the present invention comprises a rotary shaft having a convex portion provided at one end portion thereof, a sleeve which rotatably supports the rotary shaft, and having herringbone grooves formed in an inner wall thereof at positions, a thrust bearing which is provided in contact with an end portion of the rotary shaft on the convex portion side and restricts movement of the thrust bearing or the rotary shaft in an axial direction thereof, and a lubricant sealed in a space surrounded by the rotary shaft, the sleeve and the thrust bearing.

Hydrodynamic bearing for motor

A hydrodynamic bearing device of a shaft, a sleeve rotatably supporting this shaft, wherein a herringbone groove is formed at a predetermined part of an inner periphery wall face of the sleeve, and, a thrust receiver supporting a thrust side of the shaft fixed to a lower face of the sleeve, thereby sealing predetermined lubricant, wherein a spiral groove which is narrower in groove width and shallower in depth than the herringbone groove, and which is oriented to the thrust receiver in a rotation direction of the shaft, is formed on inner periphery wall face of the sleeve.

Hydrodynamic bearing device

A component rolling tool for applying a dynamic pressure groove comprising component rolling balls, cylindrical sleeve having an outer surface, an axis, a radius, a center hole, and guide holes, and being inserted into the bearing hole, and being relatively translated along the axis with respect to the bearing, and being relatively rotated about the axis with respect to the bearing, a moving roller coaxially inserted to the center hole, pressing the balls toward an outward direction of the guide holes and being moved along the axis in accordance with a pressure contact rotation between the balls and an inner peripheral surface of the bearing hole caused by a relative movement between the sleeve and the bearing, and a returning apparatus for returning the roller to an initial position at a desired timing in a state that the balls is released from a pressure contact with the inner peripheral surface.

Component rolling tool of dynamic pressure groove and component rolling method

This spindle motor has a base plate, a stator mounted on the base plate, a bearing provided on the base plate, a rotating shaft rotatably provided on the bearing, and a rotor fixed to the rotating shaft. The rotor is formed of a metallic magnetic substance and resin and is fixed to the rotating shaft at the magnetic substance, and a field magnet fixed to the rotor. The field magnet is pressed into and fixed to the rotor at a resin section of the rotor.

Spindle motor

According to a method of recording identification signals on a software recording medium of the invention, an identification signal is recorded in a left channel track of a soft tape, and an inverted signal of the identification signal is recorded in a right channel track of the soft tape. Non-inverted program signals are in the right channel and left channel tracks. For this reason, the identification signal and the inverted identification signal cancel each other in a program play mode of the soft tape.

Method of recording identification signal on software recording medium

A mode setting device for establishing various driving modes in a magnetic tape driving apparatus, comprises a cam member, and a cam guide member guided by the cam member to be shifted between a plurality of positions. And a brake member and a pinch roller are located in positions corresponding to a plurality of magnetic tape driving modes as the cam guide member is shifted between the plurality of positions.

Mode setting device of a magnetic tape driving apparatus

This invention relates to a tape cassette storage box coupling accessory. The distance between first and second lateral faces of the tape cassette storage box coupling accessory is set so that the distance between one lateral face of a first tape cassette storage box and the other lateral face of a second tape cassette storage box is substantially equal to the longitudinal length of a compact tape cassette when a second engaging means of the other lateral face of the first tape cassette storage box and the first engaging means of the one lateral face of the second tape cassette storage box are engaged with the first engaging means of the first lateral face and the second engaging means of the second lateral face of the accessory, respectively.

Tape cassette storage box coupling accessory

A magnetic head adjusting apparatus includes a base, an auxiliary base disposed over the base for supporting a magnetic head, and a first adjusting screw threadably engaged with the base to contact with its end face the surface of the auxiliary base which faces the base. The first adjusting screw moves in a direction perpendicular to the base to move the auxiliary base in the same direction, and engages the auxiliary base to support it so that the auxiliary base can rotate around the first adjusting screw axis. Second and third adjusting screws threadably engage the base at different positions to abut the surface of the auxiliary base which faces the base, and move in the direction perpendicular to the base to move the auxiliary base in the same direction. A rotating member is mounted for rotation relative to the base, and is coupled with the auxiliary base at a position offset from the axis of rotation of the rotating member relative to the base. Accordingly, the auxiliary base is rotated around the first adjusting member as the rotating member is correspondingly rotated, to adjust the magnetic head gap relative to a tape in a tape cassette next to the auxiliary base.

Magnetic head adjusting apparatus

An ejecting device which is used in a magnetic tape driving apparatus includes a first base plate extending parallel to the axes of reel shafts and at a right angle to a horizontal plane, a second base plate attached to the first base plate so as to be rotatable parallel to the first base plate between first and second positions, so that a lower portion of the second base plate below its axis of rotation relative to the first base plate is farther away from the projected ends of the reel shafts when the second base plate is located in the second position than when in the first position, a third base plate is rotatably attached to that portion of the second base plate below the axis of rotation of the second base plate relative to the first base plate, for rotation parallel to the second base plate. A tape cassette retaining member on the third base plate is provided for detachably holding the tape cassette, and a guide pin on the third base plate is fitted in a guide hole in the first base plate, so that the reel hubs of the tape cassette held by the tape cassette retaining member are mounted on the reel shafts when the second base plate is located in its first position, and the reel hubs of the tape cassette are disengaged from the reel shafts to tilt the axes of the reel hubs relative to the axes of the reel shafts while the second base plate moves from the first position to the second position.

Ejecting device of a magnetic tape driving apparatus

A tape cassette storage box comprises a storage box body for holding a micro cassette, a cover coupled with the storage box body so as to be able to rotate between a first position in which the cover houses, in cooperation with the storage box body, and micro cassette held in the storage box body and a second position in which the cover allows the micro cassette to be removed from the storage box body, and a pair of reel hub stopper members formed on the storage box body and arranged along a direction to cross the axis of rotation of the cover so as to be able to engage a pair of reel hubs of the micro cassette held in the storage box body, whereby the pair of reel hubs are prevented from rotating. The height of one of the pair of reel hub stopper members nearer to the axis of rotation than the other is is lower than that of the other.

Tape cassette storage box

A tape cassette storage box comprises a storage box body having a hollow for holding a micro cassette, a cover having a kangaroo pocket for receiving the micro cassette and coupled with the storage box body so as to be able to rotate between a first position in which the cover houses, in cooperation with the storage box body, the micro cassette held in the storage box body, and a second position in which the cover allows the micro cassette as held in the kangaroo pocket to be removed from the storage box body, and a pair of reel hub stopper members formed on the storage box body and arranged along a direction to cross the axis of rotation of the cover so as to be able to engage a pair of reel hubs of the micro cassette held in the storage box body, whereby the pair of reel hubs are prevented from rotating. The height of one of the pair of reel hub stopper members nearer to the axis of rotation than the other is lower than that of the other.

A tape guide device which is used in a magnetic tape driving apparatus employing a tape cassette, comprises a tape guide to touch two longitudinal edges of a magnetic tape in the tape cassette, thereby preventing transverse movement of the magnetic tape, when a fast-forward or fast rewinding mode is established in the magnetic tape driving apparatus.

Tape guide device of a magnetic tape driving apparatus

A tape cassette storage box comprises a first click-type engaging means disposed in a first corner region of a first lateral face of the body, a second click-type engaging means disposed in a second corner region of the first lateral face and having the same length and the same direction for engagement as those of the first click-type engaging means, a third click-type engaging means disposed in a third corner region of said first lateral face and having the same length and the same direction for engagement as those of the first click-type engaging means, and a fourth click-type engaging means disposed in a fourth corner region of the first lateral face and having the same length and the same direction for engagement as those of the first click-type engaging means, a first click-type engaging means disposed in a first corner region of a second lateral face, a second click-type engaged means disposed in a second corner region of the second lateral face and having the same length and the same direction for engagement as those of the first click-type engaged means, a third click-type engaged means disposed in a third corner region of the second lateral face and having the same length and the same direction for engagement as those of the first click-type means, and a fourth click-type engaged means disposed in a fourth corner region of the second lateral face and having the same length and the same direction for engagement as those of the first click-type engaged means.

Growing community of inventors

Tokyo, Japan

Shoichi Saito