Kataoka Corporation

Shoichi Honda

Junichi Matsumoto

Tadao Morishita

A phase difference observation apparatus includes a light source; an illumination guide to guide illumination light from the light source to an observation target object in a cell culture vessel; an optical imager to form an optical image of the observation target object on an image sensor; and a controller. The illumination guide includes a spatial modulator to change an intensity distribution of the illumination light; the controller contains intensity distribution correction information associating a position of the imaging guide with respect to the cell culture vessel with an intensity distribution of illumination light at the position of the optical imager; the controller acquires imaging system position information, which is the position of the optical imager; and the controller changes an intensity distribution of illumination light in the spatial modulator on the basis of the imaging system position information and the intensity distribution correction information.

Phase difference observation apparatus and cell treatment apparatus

The present invention is intended to provide a cell treatment apparatus and a method for treating cells that can suppress a variation of a treatment time of treating cells using laser light. The cell treatment apparatus of the present invention includes: a cell treatment chamber in which cells in a cell culture vessel are treated; an observation unit that can observe the cells; a laser projection unit that can project a laser image onto the cells; a laser moving unit that can move the laser projection unit; and a control unit. The laser projection unit includes: a laser light source; and a laser image generation portion that generates the laser image to be projected onto the cells from laser light oscillated from the laser light source. The control unit controls generation of the laser image by the laser image generation portion. By moving the laser moving unit from a projection start position of the laser image at one end of the cell culture vessel to a projection end position of the laser image at the other end of the cell culture vessel, the laser projection unit projects the laser image from the projection start position of the laser image at one end of the cell culture vessel to the projection end position of the laser image at the other end of the cell culture vessel.

Cell treatment apparatus and method for treating cells with lasers

The present invention provides a cell treatment apparatus capable of treating cells in a cell culture vessel. The cell treatment apparatusaccording to the present invention includes a first region, a second region, and a third region. The first regionand the second regionare placed in succession. The first regionis a cell treatment chamber for treating cells. The cell treatment chamber can be closed from the outside of the cell treatment chamber and includes a culture vessel placement portion for placing a cell culture vessel. The second regionincludes: a laser irradiation device capable of irradiating the cell culture vessel placed in the culture vessel placement portion with a laser; and a spot diameter adjustment device that adjusts a spot diameter formed in a portion to be irradiated with the laser in an object to be irradiated. The third regionincludes a control device that controls at least one device in the cell treatment apparatusand a power supply devicethat supplies electric power to at least one device in the cell treatment apparatus. The culture vessel placement portion is placed to be adjacent to the second regionin the cell treatment chamber. An adjacent portion to the second regionin the culture vessel placement portion is translucent.

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Kyoto, Japan

Shoichi Honda