Morishita Jintan Co., Ltd.

Fujisawa Pharmaceutical Company, Ltd.

Shohachi Tanoue

Takashi Morishita

Takehisa Hata

Hideki Sunohara

Mitio Mori

The present invention relates to a multiple soft capsule in which a soft capsule is contained in another soft capsule and the production thereof. The multiple soft capsule is useful for various industrial fields such as medicine, foods, table luxuries and the like. Especially, the multiple capsule is useful in medical field, for instance, in combining two or more components which cannot be enclosed together in a single capsule or in the dissolution control in vivo of the medicines by properly selecting the kind of the film-forming substance for the outer and inner soft capsules.

Multiple soft capsules and production thereof

Apparatus for continuously producing microcapsules which comprises at least one inner pipe for extruding a material to be encapsulated, at least one outer pipe for extruding an encapsulating material, the outer pipe being coaxially arranged around the inner pipe, means for delivering the material to be encapsuled to the inner pipe, means for delivering the encapsulating material to the outer pipe, at least one capsule-forming cylinder through which a coaxial jet flow of the material to be encapsulated and encapsulating material flows downwardly and through which a coagulating agent is forced to flow downwardly, a closed chamber which contains the coagulating agent and in which the capsule-forming cylinder is arranged vertically and means for delivering the coagulating agent to the chamber, which produces up to about 50,000 microcapsules per second per a set of the inner and outer pipes and the capsule forming cylinder.

Growing community of inventors

Amagasaki, Japan

Shohachi Tanoue