Meiji Seika Kaisha, Ltd.

Meiji Seika Pharma Co., Ltd.

Sho Takahata

Yuji Tabata

Takashi Shishikura

Maiko Iida

Makoto Ohyama

Kaori Kaneda

Yukari Hoshina

Mitsuhiro Uchida

Tomohisa Ninomiya

Ken-ichi Kawano

Ken-Ichi Kawano

An anti-fungal agent for tinea comprising as active ingredient a compound having the skeleton of 2-(1H-pyrazol-1-yl)phenol represented by the following formula (I) or (II) or a salt thereof is provided 

Topical antifungal agent

The present invention relates to a method for maintaining the remission of or treating inflammatory bowel diseases, which comprises administering a maintenance therapeutically effective amount or a therapeutically effective amount of 7,8-dimethoxy-4(5H),10-dioxo-1H-1,2,3-triazolo[4,5-c][1]benzoazepine, a prodrug thereof, or a pharmaceutically acceptable salt thereof to a mammal, wherein the prodrug is 2-(1-isopropoxycarbonyloxy-2-methylpropyl)-7,8-dimethoxy-4(5H),10-dioxo-2H-1,2,3-triazolo[4,5-c][1]benzoazepine. The method according to the present invention is effective in the maintenance therapy and therapy of the inflammatory bowel diseases and has few side effects. Particularly, the method according to the present invention may exhibit strong maintenance therapeutic and therapeutic effects, even on severe cases having resistance to the conventional therapeutics.

Therapeutic agent for inflammatory bowel diseases

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Yokohama, Japan

Sho Takahata