Fujifilm Corporation

Sho Onozawa

Sohichiro Nakamura

Ryusuke Osaki

Hirotaka Ito

Takeshi Unemura

Akihiro Asakura

A determination method of non-destructively and easily determining a state of an aggregate of a plurality of cells formed by three-dimensional culture is provided. A determination method according to the disclosed technology includes generating a phase difference image of an aggregate of a plurality of cells from a hologram obtained by imaging the aggregate, deriving a phase difference amount density by dividing a total phase difference amount that is a value obtained by integrating a phase difference amount of each of a plurality of pixels constituting the phase difference image by a volume of the aggregate, and determining a state of the aggregate on the basis of a time transition of the phase difference amount density.

Determination method

Provided is a determination method capable of non-destructively and simply determining a state of a sphere that is an aggregate of a plurality of cells. A phase difference image of a sphere that is an aggregate of a plurality of cells is generated from a hologram obtained by imaging the sphere, and a state of the sphere is determined on the basis of the phase difference image and a shape index value corresponding to a shape of the sphere.

Method for determining a state of a sphere

A determination method of non-destructively and easily determining a state of an aggregate of a plurality of cells formed by three-dimensional culture is provided. A determination method according to the disclosed technology includes generating a phase difference image of an aggregate of a plurality of cells from a hologram obtained by imaging the aggregate, deriving a first index value that indicates a randomness of an array of a phase difference amount in a plurality of pixels constituting the phase difference image, and determining a state of the cells constituting the aggregate on the basis of the first index value.

An image processing apparatus includes an acquisition unit that acquires a hologram obtained by imaging a plurality of granules contained within an imaging visual field, a generation unit that generates, from the hologram, phase difference images at positions different from each other in an optical axis direction in a case in which the hologram is captured, a specifying unit that specifies a plurality of image ranges in a direction of a plane intersecting the optical axis direction, which correspond to the plurality of granules, in an averaged image obtained by averaging at least some of the phase difference images, and an extraction unit that extracts the phase difference image at a center position of a corresponding granule in the optical axis direction for each of the plurality of image ranges.

Image processing apparatus, evaluation system, image processing program, and image processing method

A blood flow analysis device includes a blood vessel region extraction unit that extracts a blood vessel region from a three-dimensional medical image of a subject including a blood vessel, and a blood flow simulation unit that obtains a line resistance by multiplying a resistance value corresponding to a branch blood vessel branching out of the blood vessel region by a surface area of each of preset sections into which the blood vessel region is divided in an extension direction, generates a vascular network model by applying the line resistance to each node of a surface of the blood vessel region, and performs simulation of a blood flow by using the vascular network model.

Blood flow analysis device, method, and program

The liquid ejection method of ejecting liquid from a nozzle, includes the steps of: growing a column of the liquid from the nozzle; and injecting a bubble into a base of the column of the liquid during growth thereof from the nozzle, by using a bubble supply device which supplies a bubble.

Liquid ejection method, liquid ejection head and liquid ejection apparatus

The mist ejection head comprises: a nozzle ejecting a liquid in a form of a mist; a liquid chamber connected to the nozzle; an ultrasonic wave generating element which is disposed on a side wall of the liquid chamber and which generates an ultrasonic wave in such a manner that the ultrasonic wave is applied to the liquid inside the liquid chamber; and a reflector having a reflecting surface which reflects the ultrasonic wave generated by the ultrasonic wave generating element in such a manner that the ultrasonic wave is directed toward a center of the liquid chamber and concentrated at a focal point situated in a vicinity of the nozzle inside the liquid chamber.

Mist ejection head and image forming apparatus

The mist spraying apparatus includes: a liquid chamber filled with liquid; a mesh member which is disposed on a liquid ejection side of the liquid chamber, has a net shape, and retains a free surface of the liquid filled in the liquid chamber, the mesh member including an intersection point to form the net shape; and an ultrasonic wave generating device which is disposed at a position opposing the intersection point of the mesh member and emits an ultrasonic wave into the liquid.

Mist spraying apparatus and image forming apparatus

The mist ejection head has: a nozzle plate in which a nozzle hole for ejecting liquid is formed; a liquid chamber connected to the nozzle hole; an ultrasonic wave generating device which applies an ultrasonic wave to the liquid in the liquid chamber; and a reflective wall which reflects the ultrasonic wave applied to the liquid, wherein: the reflective wall is disposed so as to oppose the nozzle plate and has an axially symmetrical shape comprising a portion of a parabolic surface, the portion including an apex of the parabolic surface and being on an apex side with respect to a focal point of the parabolic surface; an axis of the parabolic surface passes through the nozzle hole; and the focal point of the parabolic surface is positioned in a vicinity of the nozzle hole.

Mist ejection head, image forming apparatus comprising mist ejection head, and liquid ejection apparatus comprising mist ejection head

The liquid ejection head includes: a liquid flow channel of which at least one wall is constituted by an elastic member; a nozzle which is provided at an end of the liquid flow channel; and a pressure generating device which generates a pressure pulse wave in liquid inside the liquid flow channel. The liquid flow channel and the pressure generating device are composed in such a manner that the pressure pulse wave propagates as a soliton through the liquid in the liquid flow channel.

Liquid ejection head and image forming apparatus

The liquid ejection apparatus includes: a pressure chamber which contains liquid; a nozzle which is connected to the pressure chamber, the liquid being ejected in an ejection direction through the nozzle; a piezoelectric element which applies pressure change to the liquid in the pressure chamber, a part of the liquid protruding from the nozzle upon the pressure change and growing into a column of the liquid having a longitudinal direction parallel with the ejection direction; an electrode which induces a charge on a surface of the column of the liquid; and a voltage control device which controls voltage applied to the electrode, the voltage control device reversing polarity of the electrode when the column of the liquid has grown to a prescribed length.

Liquid ejection apparatus, liquid ejection method and image forming apparatus

The mist ejection head includes: a nozzle which ejects liquid; a nozzle plate which has electrical conductivity and in which the nozzle is formed; a liquid chamber connected to the nozzle; an ultrasonic wave generating element which generates an ultrasonic wave applied to the liquid in a vicinity of the nozzle; and an electrode which is provided on a wall of the liquid chamber other than the nozzle plate, wherein an electric field applied between the nozzle plate and the electrode is controlled.

Mist ejection head and image forming apparatus comprising same

The mist spraying apparatus includes: a liquid chamber into which liquid is filled; an ejection port through which the liquid is ejected from the liquid chamber; a first electrode which is in contact with the liquid and charges the liquid; a vibration generating device which converts the liquid into droplets by applying vibrational energy to the liquid inside the liquid chamber, thereby generating a charged mist; a rear surface electrode which is disposed so as to oppose an ejection surface including the ejection port, and holds a liquid receiving medium onto which the charged mist is deposited from the ejection port; and a second electrode which is disposed at a position in an outward radial direction from an edge of the ejection port, and generates an electric field between the second electrode and the rear surface electrode, the electric field accelerating and converging the charged mist ejected from the ejection port toward the liquid receiving medium.

Mist spraying apparatus and method, and image forming apparatus

The mist spraying apparatus comprises: a liquid chamber into which liquid is filled; a coil which is applied with an electrical signal to generate a magnetic filed, the electrical signal having a frequency corresponding to an ultrasonic wave; a diaphragm which is vibrated by the magnetic field generated by the coil, and imparts the ultrasonic wave to the liquid in the liquid chamber; a spraying port which is connected to the liquid chamber and sprays the liquid converted into a mist by the ultrasonic wave; and a drive unit which applies the electrical signal to the coil.

The liquid ejection head has: a surface acoustic wave propagation body in which a surface acoustic wave propagates; a nozzle orifice formed in the surface acoustic wave propagation body; a surface acoustic wave generation device which is provided on the surface acoustic wave propagation body around the nozzle orifice and excites the surface acoustic wave propagation body so that a surface acoustic wave is generated in the surface acoustic wave propagation body; a liquid supply device which supplies liquid to the nozzle orifice; and a guide member which is provided in a center of the nozzle orifice and has a tapered conical surface shape section that projects from an ejection surface of the nozzle orifice in an ejection direction, the liquid forming a curved liquid surface in the nozzle orifice in accordance with the tapered conical surface shape section due to surface tension, wherein the surface acoustic wave generates a capillary wave which propagates through the curved liquid surface in the nozzle orifice and which ejects the liquid from an apex section of the tapered conical surface shape section.

Growing community of inventors

Kanagawa-ken, Japan

Sho Onozawa