Tel Aviv University

Technology Innovation Momentum Fund (israel) Limited Partnership

Technology Innovation Momentum Fund (isreal) Limited Partnership

Shmuel Einav

Ehud Gazit

Zvi Nevo

Ludmila Buzhansky

Lihi Adler-Abramovich

Moran Aviv

Giora Amitzur

Eran Peleg

Elya Zimerman

Ifat Lavi

Ran Kornowski

Ariel Sverdlik

Oren Rotman

Zeev Aronis

Zehava Ovadia-Blechman

Michael Eldar

Described is a method of stabilizing blood vessel wall abnormality. The method includes ultrasonically heating at least a portion of the blood vessel wall having the abnormality; monitoring a parameter related to a property of at least a portion of the heated portion of the blood vessel wall; and stopping the heating when the monitored parameter changes by a predetermined factor or after the monitored parameter changes in a slow enough rate. The slow enough rate may be, for instance, a predetermined fraction of a maximal rate change observed during heating.

Treating weakened vessel wall such as vulnerable plaque or aneurysms

Hybrid hydrogels formed of a plurality of peptides that are capable of self-assembling into a hydrogel in an aqueous solution and a biocompatible polymer that is characterized by high swelling capability, high elasticity and low mechanical strength are disclosed, with exemplary hybrid hydrogels being formed of a plurality of aromatic dipeptides and hyaluronic acid. The hybrid hydrogels are characterized by controllable mechanical and biological properties which can be adjusted by controlling the concentration ratio of the peptides and the polymer, and which average the mechanical and biological properties of the peptides and the polymer. Processes of preparing the hydrogels and uses thereof in pharmaceutical, cosmetic or cosmeceutic applications such as tissue engineering and/or regeneration are further disclosed.

Malleable hydrogel hybrids made of self-assembled peptides and biocompatible polymers and uses thereof

Catheter cannula, catheter, and catheterization method, for administering a fluid or/and substance to, or for draining a fluid or/and substance from, a treatment space of a body vessel, duct, or cavity. In some embodiments the cannula includes: an elongated flexible tube mountable on a needle, and having an invasive section and a non-invasive section; and at least one anchoring element protruding from, a surface of the invasive section in a manner such that an operative configuration of each anchoring element increases outer circumferential diameter of the cannula to an extent less than lumen diameter of the body vessel, duct, or cavity, at the treatment space, thereby anchoring the invasive section to inside the body vessel, duct, or cavity, at the treatment space. The catheter includes a needle and the cannula mounted thereupon.

Catheter cannula with anchoring elements, catheter including thereof, and/or catheterization method using thereof

A method of determining endothelial dependent vasoactivity of a subject, the method is effected by recording pressure-related signals of a plurality of locations adjacent to at least one blood vessel; extracting at least one parameter from the pressure-related signals; and using the at least one parameter to determine a change of at least one characteristic of the at least one blood vessel, the change being representative of endothelial functioning; thereby determining the endothelial dependent vasoactivity of the subject.

System for determining endothelial dependent vasoactivity

The invention provides a method for determining the degree of partial occlusion of a conduit, comprising the steps of:

Method for determining the degree of occulsion and elasticity in blood

Growing community of inventors

Herzlia, Israel

Shmuel Einav