Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

Tel Aviv University

Bioimmunate Technologies Ltd.

Shlomo Yitzchaik

Micha E Spira

Joseph Shappir

Uri Banin

Yael Hanein

Ori Cheshnovsky

Evelyne Sernagor

Sigalit Carmel

Shimon Shteingart

Evgenia Vaganova

Hadar Amartely

Omri Shmuel Alfassy

Elza Snir

Vladimir Burtman

Micha Spira

Biological filters for removing target components from biological fluids such as removal of pathogenic cells from whole blood, are described. The filters may include a medium comprising an inert surface, with capture material disposed on the inert surface. The filter may be configured to selectively recognize, capture, and remove target cells such as pathogenic cells associated with a disease, such as an autoimmune disease or cancer. Devices, systems, apparatuses, computer readable media, and methods associated with biological filtering are also provided.

Filter for removal of multiple sclerosis-associated t-cells

Provided are thermo-sensitive and light-sensitive polymer compositions including poly(4-vinyl pyridine) and poly(4-vinyl pyridine-co-butyl methacrylate).

Polymeric compositions and uses thereof

The present invention provides a novel photoelectrical device for efficient transmission of electrical signals to a neuron. This photoelectrical device comprises one or more charging units for coupling to and stimulating one or more neurons by charge, the charging unit comprising: a nanostructure-based electrode having a surface, which has a predetermined developed surface area for coupling to a neuron and which carries a plurality of photosensitive regions (e.g. quantum dots) interfacing with a biocompatible macromolecule for tuning the relative energy levels between the photosensitive regions and the electrode, as well as for directing the spatial polarity of charge separation the surface being thereby electrically chargeable and dischargeable in response to light excitation of the photosensitive regions, the charges stimulating the neuron when coupled to the surface.

Photoelectrical devices for stimulating neurons

The present invention provides a surface-substrate for adherence of cells thereto. The surface-substrate comprises at least one micronail structure protruding from the surface, at least a region of the micronail having cellular-internalization promoting properties. The invention also provides an electronic device comprising a transistor structure, in which a gate electrode is formed with the at least one micronail protruding from the surface thereof.

Electronic device for communication with living cells

Organic superlattices formed by molecular layer epitaxy (MLE), and a novel MLE method of forming organic molecular monolayers are disclosed. The method utilized covalent linkage, combined with self-cleaning layer growth, to form pi-stacked, ordered, oriented monomolecular layers for use in a variety of electronic applications.

Molecular epitaxy method and compositions

Organic superlattices fromed by molecular layer epitaxy (MLE), and a novel MLE method of forming organic molecular monolayers are disclosed. The method utilized covalent linkage, combined with self-cleaning layer growth, to form pi-stacked, ordered, oritented monomolecular layers for use in a variety of electronic applications.

Molecular layer epitaxy method and compositions

The present invention concerns an electrical junction between one transistor and at least one voltage sensitive cell such as a neuron. The invention further concerns transistors to be used in said junction and methods for their preparation. By another aspect the invention concerns &ldquo;an artificial chemical synapse&rdquo; i.e. a junction between a cell, which secretes an agent, and a transistor bearing receptors for the agent, wherein binding of the agent to the receptor changes an electrical property off the transistor.

Hybrid electrical device with biological components

Organic superlattices formed by chemical vapor deposition/molecular layer epitaxy (CVD/MLE), and a novel CVD/MLE method of forming organic molecular monolayers are disclosed. The method utilized covalent linkage, combined with layer sublimation, to form p-stacked, ordered, oriented monomolecular layers for use in a variety of electronic applications.

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Jerusalem, Israel

Shlomo Yitzchaik