Daicel Corporation

Shizuka Ukita

Toshikazu Nakamura

Shu Shimamoto

Tsuyoshi Nakamura

Hiroshi Kobayashi

Ryoko Yamauchi

Hiroki Taniguchi

Tomohiro Hashizume

Tatsuya Morita

Tomomi Genda

A nutrient composition contains a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may have a compositional distribution index (CDI) of 2.0 or less, where the CDI is specified by the formula:=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition)where the measured value of half height width of chemical composition represents the half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample); and[Math. 1]the theoretical value of half height width of chemical composition=2.35482&#x221a;{square root over (3**(3)*(1&#x2212;3))}/where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

Nutrient composition having lipid metabolism-improving action

A cellulose acetate according to the present invention has a total degree of acetyl substitution of 0.4 to 1.1 and has a compositional distribution index (CDI) of 3.0 or less, where the CDI is specified by the formula:CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition)where the measured value of half height width of chemical composition is a half height width of chemical composition determined by analyzing a cellulose acetate propionate by HPLC, where the cellulose acetate propionate is prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample); andTheoretical value of half height width of chemical composition=2&#xb7;35482&#x221a;{square root over (3**(/3)*(1&#x2212;/3))}/&#x2003;&#x2003;[Math. 1]where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

Cellulose acetate with a low degree of substitution

Provided is a novel cellulose derivative having excellent water resistance. This is a cellulose acylate oxoalkanoate which is a cellulose derivative corresponding to cellulose, except with substituents replacing part or all of hydrogen atoms in the hydroxy groups of the cellulose. The substituents includes a group represented by General Formula (1) and a group represented by General Formula (2). The cellulose acylate oxoalkanoate has a degree x of substitution with the group represented by General Formula (1), a degree y of substitution with the group represented by General Formula (2), and a degree z of unsubstitution, where x, y, and z meet conditions specified by Expressions (A), (B), and (C):0.1&#x2264;&#x2264;2.99&#x2003;&#x2003;(A)0.01&#x2264;&#x2264;2.90&#x2003;&#x2003;(B)=3&#x2212;&#x2003;&#x2003;(C) 

Cellulose acylate-oxoalkanoate

A nutrient composition, a lipid metabolism-improving agent, and prophylactic and/or therapeutic agents typically for inflammatory bowel diseases, immune disorders, cancers, non-alcoholic steatohepatitis, obesity, diabetes, and hypercholesterolemia each contain a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may be one having a compositional distribution index (CDI) of 2.0 or less, where the CDI is defined by the formula:CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition)

Nutritional composition

A nutrient composition contains a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may have a compositional distribution index (CDI) of 2.0 or less, where the CDI is specified by the formula:CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition)where the measured value of half height width of chemical composition represents the half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample); andthe theoretical value of half height width of chemical composition=2.35482&#x221a;{square root over (3**(/3)*(1&#x2212;/3))}/&#x2003;&#x2003;[Math. 1]where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

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Himeji, Japan

Shizuka Ukita