Wockhardt Limited

Shivaji Sampatrao Pawar

Prasad Keshav Deshpande

Satish B Bhawsar

Mahesh Vithalbhai Patel

Sunil Bhaginath Jadhav

Sachin Subhash Bhagwat

Ravindra Dattatraya Yeole

Ravikumar Tadiparthi

Deepak Dekhane

Vijaykumar Jagdishwar Patil

Satish Shrimant Birajdar

Piyush Ambalal Patel

Mohammad Usman Shaikh

Vikas Vitthalrao Deshmukh

Sanjay Kisan Dabhade

Bharat Kalidas Trivedi

Amit Chandra Mishra

Sanjeev Joshi

Karuna Suresh Wankhede

Bharat Dhond

Santosh Diwakar

Vinod Kashinath Ahirrao

Milind Dattatraya Sindkhedkar

Sunil Gupta

Mohammad Alam Jafri

Bharat Dond

Vipul Rane

Satish Bhavsar

Vijaya Narayan Desai

Vijay Patil

Manish Solanki

Rajesh Maganlal Loriya

Rajesh Onkardas Bora

Ganesh Rajaram Jadhav

Bharat Trivedi

Satish Birajdar

A process for preparation of (2S, 5R)-7-oxo-6-sulphooxy-2-[((3R)-piperidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo[3.2.1]octane is disclosed.

Process for preparation of (2S, 5R)-7-oxo-6-sulphooxy-2-[((3R)-piperidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo [3.2.1]-octane

A process for preparation of (2S,5R)-7-oxo-6-sulphooxy-2-[((3R)-piperidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo[3.2.1]octane of Formula (I) is disclosed which is comprising reacting a compound of Formula (II) with a compound of Formula (III) to obtain a compound of Formula (IV). Crystalline compounds of Formula (I) are claimed. 

Process for preparation of (2S, 5R)-7-oxo-6-sulphooxy-2[((3R)-piperidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo [3.2.1]-octane

A process for preparation of (2S,5R)-7-oxo-6-sulphooxy-2-[((3R)-pyrrolidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo[3.2.1]octane is disclosed comprising reacting a compound of Formula (II) with a compound of Formula (III) to obtain a compound of Formula (IV). The crystalline end-product is als claimed.

Process for preparation of (2S, 5R)-7-oxo-6-sulphooxy-2-[((3R)-pyrrolidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo[3.2.1]octance

Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed. 

Nitrogen containing heterocyclic compounds

Compound of Formula (I), its preparation and use in preventing or treating bacterial infection is disclosed. Formula (I) 

Nitrogen containing compounds and their use

The invention relates to ketolide compounds of Formula (I) and their pharmaceutically acceptable salts, solvates, hydrates, polymorphs and stereoisomers having antimicrobial activity. The invention also provides pharmaceutical compositions containing the compounds of invention and methods of treating or preventing microbial infections with the compounds of invention, wherein, T is &#x2014;C*H(R)&#x2014;P-Q; Ris hydrogen; unsubstituted or substituted lower alkyl, cycloalkyl or aryl; P is heteroaryl ring; Q is unsubstituted or substituted aryl or heteroaryl ring; and P is attached to Q via carbon-carbon link; and Ris hydrogen or fluorine, With the provision that when Ris hydrogen, Ris fluorine. 

Ketolide compounds

1,6-diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections

The present invention provides compounds having antimicrobial activity for preventing and treating diseases caused by microbial infections. Thus, the present invention relates to novel semi-synthetic 11,12-&#x3b3; lactone macrolides and ketolides having antimicrobial activity, processes for making compounds as well as pharmaceutical compositions containing said compounds as active ingredients and methods of treating microbial infections with the compounds.

Macrolides and ketolides having antimicrobial activity

Growing community of inventors

Aurangabad, India

Shivaji Sampatrao Pawar