Siemens Medical Solutions USA, Inc.

Shishir Dube

Gerardo Hermosillo Valadez

Yoshihisa Shinagawa

Sarang Lakare

Described herein is a method and system for facilitating segmentation of images. A difference image is received and processed to extract at least one histogram (). A noise component is determined by fitting a symmetric Gaussian distribution to the extracted histogram such that the negative portion of the Gaussian distribution coincides with the negative portion of the histogram (). The noise component is then subtracted from the histogram to generate a probability distribution function (), which may be converted to a cumulative distribution function () and applied to the difference image to generate a probabilistic representation of contrast enhancement ().

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Arden, NC, United States of America

Shishir Dube