Shionogi Company Limited

Shiro Ueda

Ichiro Ishizuka

Hiroyuki Kai

Shinzaburo Sumimoto

Akira Takase

Kazuyuki Sasakura

Tsutomu Sugasawa

Kinya Ide

Tatsuo Toyoda

Sumimoto Shinzaburo

Katsuto Okuno

A novel compound useful as an intermediate for synthesizing pesticides and medicine of the formula: ##STR1## in which: R is perfluoroalkyl, R.sup.1 is hydrogen, alkyl or optionally substituted phenyl, or a salt thereof.

3-perfluoroalkyl-5-hydroxyisoxazoles

A fluorinated .beta.-ketonitrile of the formula: ##STR1## in which: R is alkyl having plural fluorines and R.sup.1 is hydrogen or alkyl.

.beta.-ketonitrils

A novel herbicidal compound of the formula: ##STR1## in which R is OH, C.sub.1 -C.sub.3 alkoxy or R.sup.3 -N-R.sup.4 ; R.sub.f is C.sub.1 -C.sub.3 perfluoroalkyl; R.sup.1 is hydrogen, C.sub.1 -C.sub.6 alkyl or optionally substituted phenyl; R.sup.2 is hydrogen or C.sub.1 -C.sub.3 alkyl; n is an integer of 0 to 2; R.sup.3 is hydrogen or C.sub.1 -C.sub.3 alkyl; R.sup.4 is C.sub.1 -C.sub.6 alkyl, optionally substituted phenylalkyl where alkyl contains 1 to 3 carbons or optionally substituted phenyl; or R.sup.3 and R.sup.4 together with the nitrogen atom to which they are attached form a cyclic amino group; or a salt thereof. A process for preparing the compound (I) and a herbicide containing the compound (I) are also disclosed.

3-perfluoroalkyl-5-substituted-oxy-isoxazole derivatives, process for

A novel compound useful as an intermediate for synthesizing pesticides and medicines of the formula: ##STR1## in which: R is alkyl having plural florines; R.sup.1 is hydrogen, alkyl, halogen or optionally substituted phenyl; and R.sup.2 is hydrogen or alkyl, or a salt thereof.

Polyfluoroalkylisoxazolylamines

Cyanopinacolone is produced by reacting pinacolone with about 1.0 to about 1.2 molar equivalents of chlorine in methanol and further reacting the resulting monochloropinacolone with about 1.0 to about 1.2 molar equivalents of an alkali metal cyanide in methanol.

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Osaka, Japan

Shiro Ueda