Dyax Corporation

Takeda Pharmaceutical Company Limited

Shirish Hirani

Robert Charles Ladner

Arthur Charles Ley

Anthony Williams

Luigi Bergamaschini

Maria Grazia De Simoni

Henry Blair

Maria Grazia Simoni

Thomas Beck

Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.

Prevention and reduction of blood loss

Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.

Kallikrein-inhibitor therapies

Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g., coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.

Growing community of inventors

Arlington, MA, United States of America

Shirish Hirani